HitPredict

Interactor 1: RPF1 (P38805)
Ribosome production factor 1 (Ribosome biogenesis protein RPF1)
Gene: RPF1

Interactor 2: HAS1 (Q03532)
ATP-dependent RNA helicase HAS1 (EC 3.6.4.13) (Helicase associated with SET1 protein 1)
Gene: HAS1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.88	0.60	0.729

Property	Details
Experiments	11805826, 30568249, 31511893, 16429126, 29557065, 37968396
Identification Methods	tandem affinity purification, affinity chromatography technology, biochemical, x-ray crystallography
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000463 - maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) GO:0005730 - nucleolus GO:0030687 - preribosome, large subunit precursor
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 295 Sc			1 505
+	Sc
		593679 IMP4_YEAST (22-295): 1.85e-108: 318: 26.96		DBP4_YEAST (3-501): 9.9e-165: 486: 37.70
+	Sc
		866605 IMP4_YEAST (22-295): 1.85e-108: 318: 26.96		HAS1_YEAST (1-505): 1.8e-165: 479: 100.00
+	Sc
		699680 RPF1_YEAST (1-295): 8.87e-130: 372: 100.00		DRS1_YEAST (26-394): 3.8e-72: 245: 38.32
+	Sc
		638747 RPF1_YEAST (1-295): 8.87e-130: 372: 100.00		SPB4_YEAST (56-488): 1.9e-61: 213: 33.41