HitPredict

Interactor 1: BZZ1 (P38822)
Protein BZZ1 (LAS17-binding protein 7)
Gene: BZZ1

Interactor 2: END3 (P39013)
Actin cytoskeleton-regulatory complex protein END3 (Endocytosis protein 3)
Gene: END3

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	19841731
Identification Methods	two hybrid, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0006897 - endocytosis GO:0007015 - actin filament organization GO:0030479 - actin cortical patch and 1 others more... GO:0043332 - mating projection tip
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 633 Sc			1 349
+	Hs
		787902 FCHO2_HUMAN (4-607): 2.18e-49: 186: 12.42		EPS15_HUMAN (10-348): 7.95e-34: 134: 15.69
+	Hs
		1001598 FCHO2_HUMAN (4-607): 2.18e-49: 186: 12.42		EP15R_HUMAN (12-274): 5.5e-32: 128: 17.60
+	Hs
		1078897 FNBP1_HUMAN (5-633): 2.15e-66: 230: 14.22		ITSN1_HUMAN (124-241): 2.14e-09: 61.1: 12.30
+	Hs
		1078872 ITSN1_HUMAN (16-633): 1.19e-25: 115: 10.79		REPS2_HUMAN (3-348): 2.13e-47: 171: 16.89
+	Hs
		298006 FCSD2_HUMAN (13-633): 6.3e-56: 204: 14.83		ITSN2_HUMAN (3-349): 5.91e-15: 78.1: 12.53
+	Hs
		1203306 FCSD1_HUMAN (10-633): 3.72e-50: 187: 13.45		ITSN2_HUMAN (3-349): 5.91e-15: 78.1: 12.53
+	Hs
		297971 FCSD2_HUMAN (13-633): 6.3e-56: 204: 14.83		ITSN1_HUMAN (124-241): 2.14e-09: 61.1: 12.30
+	Hs
		61732 A6H8W8_HUMAN (19-633): 2.26e-26: 117: 12.84		EPS15_HUMAN (10-348): 7.95e-34: 134: 15.69
+	Hs
		787920 ITSN1_HUMAN (16-633): 1.19e-25: 115: 10.79		EPS15_HUMAN (10-348): 7.95e-34: 134: 15.69
+	Hs
		1001577 FCHO2_HUMAN (4-607): 2.18e-49: 186: 12.42		ITSN1_HUMAN (124-241): 2.14e-09: 61.1: 12.30
+	Hs
		787985 ITSN2_HUMAN (19-633): 7.25e-25: 112: 12.82		EPS15_HUMAN (10-348): 7.95e-34: 134: 15.69
+	Hs
		61738 A6H8W8_HUMAN (19-633): 2.26e-26: 117: 12.84		EP15R_HUMAN (12-274): 5.5e-32: 128: 17.60
+	Cl
		47357 F1PHV6_CANLF (16-633): 1.22e-25: 115: 11.47		A0A8I3PJA6_CANLF (10-348): 3.4e-32: 129: 14.89
+	Hs
		1078923 ITSN1_HUMAN (16-633): 1.19e-25: 115: 10.79		EP15R_HUMAN (12-274): 5.5e-32: 128: 17.60
+	Hs
		1349279 ITSN2_HUMAN (19-633): 7.25e-25: 112: 12.82		EP15R_HUMAN (12-274): 5.5e-32: 128: 17.60
+	Rn
		92844 ITSN1_RAT (16-633): 2.91e-26: 117: 11.82		E9PSY8_RAT (23-223): 3.8e-29: 120: 20.90
+	Hs
		1078919 ITSN1_HUMAN (16-633): 1.19e-25: 115: 10.79		ITSN2_HUMAN (3-349): 5.91e-15: 78.1: 12.53
+	Hs
		1349275 ITSN2_HUMAN (19-633): 7.25e-25: 112: 12.82		ITSN2_HUMAN (3-349): 5.91e-15: 78.1: 12.53
+	Hs
		1078828 ITSN1_HUMAN (16-633): 1.19e-25: 115: 10.79		ITSN1_HUMAN (124-241): 2.14e-09: 61.1: 12.30