Protein: NUF2
Kinetochore protein NUF2

Gene: NUF2
Organism: Saccharomyces cerevisiae S288C
Interactions: 137
UniProt ID: P33895

Gene Ontology (top 5):
GO:0000776 - kinetochore
GO:0000779 - condensed chromosome, centromeric region
GO:0000940 - outer kinetochore
GO:0005634 - nucleus
GO:0005816 - spindle pole body

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

755249

NDC80
Kinetochore protein NDC80

28

18

Small-scale

0.993

High

755297

SPC24
Kinetochore protein SPC24

13

0

Small-scale

0.931

High

755250

DSN1
Kinetochore-associated protein DSN1

13

0

Small-scale

0.725

High

755278

MPS1
Serine/threonine-protein kinase MPS1

5

5

Small-scale

0.713

High

755242

SPC25
Kinetochore protein SPC25

6

0

Small-scale

0.706

High

755255

CENPT
Inner kinetochore subunit CNN1

4

0

Small-scale

0.661

High

755271

KNL1
Outer kinetochore KNL1 complex subunit SPC105

3

1

Small-scale

0.658

High

755238

MTW1
Kinetochore-associated protein MTW1

3

1

Small-scale

0.658

High

602040

KAR3
Kinesin-like protein KAR3

3

5

High-throughput

0.656

High

755258

STU2
Protein STU2

3

3

Small-scale

0.651

High

755304

BRE1
E3 ubiquitin-protein ligase BRE1

3

13

High-throughput

0.645

High

755263

NNF1
Kinetochore-associated protein NNF1

3

0

Small-scale

0.630

High

755225

JNM1
Nuclear migration protein JNM1

3

0

High-throughput

0.628

High

755292

SPC19
DASH complex subunit SPC19

3

0

Small-scale

0.627

High

755232

CENPU
Inner kinetochore subunit AME1

3

0

Small-scale

0.622

High

755302

HDA2
HDA1 complex subunit 2

3

0

High-throughput

0.617

High

755218

NUF2
Kinetochore protein NUF2

2

13

Small-scale

0.609

High

755318

GIN4
Serine/threonine-protein kinase GIN4

2

11

High-throughput

0.595

High

724285

ZIP1
Synaptonemal complex protein ZIP1

3

2

High-throughput

0.589

High

755223

SPC42
Spindle pole body component SPC42

2

0

High-throughput

0.587

High

755281

DAD4
DASH complex subunit DAD4

2

0

Small-scale

0.583

High

755268

KEL2
Kelch repeat-containing protein 2

3

2

High-throughput

0.580

High

755275

DAM1
DASH complex subunit DAM1

2

0

Small-scale

0.577

High

755311

SGO1
Shugoshin

2

0

High-throughput

0.561

High

755224

SPC34
DASH complex subunit SPC34

2

0

Small-scale

0.560

High

755294

ECM11
Protein ECM11

2

0

High-throughput

0.559

High

755233

KPR2
Ribose-phosphate pyrophosphokinase 2

2

5

Small-scale

0.543

High

755282

NUM1
Nuclear migration protein NUM1

2

9

High-throughput

0.543

High

755269

HUL5
E3 ubiquitin-protein ligase HUL5

1

2

High-throughput

0.541

High

755254

SA155
SIT4-associating protein SAP155

1

1

High-throughput

0.536

High

755229

STU1
Protein STU1

1

0

High-throughput

0.518

High

548193

BIK1
Nuclear fusion protein BIK1

1

4

High-throughput

0.515

High

753056

NIP80
Protein NIP100

1

16

High-throughput

0.515

High

755315

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.513

High

555245

RAD50
DNA repair protein RAD50

1

5

High-throughput

0.508

High

699396

CIN8
Kinesin-like protein CIN8

1

9

High-throughput

0.508

High

747715

SMC1
Structural maintenance of chromosomes protein 1

1

4

High-throughput

0.508

High

755261

SMC3
Structural maintenance of chromosomes protein 3

1

6

High-throughput

0.508

High

755320

SMC4
Structural maintenance of chromosomes protein 4

1

4

High-throughput

0.508

High

755285

CENPP
Inner kinetochore subunit CTF19

1

0

High-throughput

0.493

High

755300

NKP2
Inner kinetochore subunit NKP2

1

0

High-throughput

0.493

High

753014

SPC29
Spindle pole component 29

1

0

High-throughput

0.486

High

448690

SNF1
Carbon catabolite-derepressing protein kinase

1

4

High-throughput

0.481

High

598390

TUP1
General transcriptional corepressor TUP1

1

8

High-throughput

0.481

High

665802

KPC1
Protein kinase C-like 1

1

4

High-throughput

0.481

High

750222

PRP40
Pre-mRNA-processing protein PRP40

1

1

High-throughput

0.481

High

755222

BDF1
Bromodomain-containing factor 1

1

5

High-throughput

0.481

High

755228

ISW1
ISWI chromatin-remodeling complex ATPase ISW1

1

2

High-throughput

0.481

High

755240

LIS1
Nuclear distribution protein PAC1

1

7

High-throughput

0.481

High

755257

SAC3
Nuclear mRNA export protein SAC3

1

1

High-throughput

0.481

High

755260

SET2
Histone-lysine N-methyltransferase, H3 lysine-36 specific

1

3

High-throughput

0.481

High

755264

HMS2
Probable transcription factor HMS2

1

1

High-throughput

0.481

High

755270

ITC1
Imitation switch two complex protein 1

1

1

High-throughput

0.481

High

755286

FCP1
RNA polymerase II subunit A C-terminal domain phosphatase

1

2

High-throughput

0.481

High

755288

NHP10
Non-histone protein 10

1

4

High-throughput

0.481

High

755307

ADY3
Accumulates dyads protein 3

1

13

High-throughput

0.481

High

755310

SMC5
Structural maintenance of chromosomes protein 5

1

9

High-throughput

0.481

High

755313

YP216
Putative ISWI chromatin-remodeling complex subunit YPL216W

1

1

High-throughput

0.481

High

755220

ASK1
DASH complex subunit ASK1

1

0

Small-scale

0.480

High

755280

DAD3
DASH complex subunit DAD3

1

0

Small-scale

0.480

High

755312

SLK19
Kinetochore protein SLK19

1

10

High-throughput

0.479

High

477541

MYO1
Myosin-1

1

4

High-throughput

0.470

High

735607

SMY1
Kinesin-related protein SMY1

1

5

High-throughput

0.470

High

755287

VPS60
Vacuolar protein-sorting-associated protein 60

1

3

High-throughput

0.470

High

743008

SWI3
SWI/SNF complex subunit SWI3

1

0

High-throughput

0.460

High

749653

TYE7
Transcription factor TYE7

1

0

High-throughput

0.460

High

750611

PRS6A
26S proteasome regulatory subunit 6A

1

0

High-throughput

0.460

High

755230

RXT2
Transcriptional regulatory protein RXT2

1

0

High-throughput

0.460

High

755237

MBO1
Gamma tubulin complex adapter SPC72

1

0

High-throughput

0.460

High

755245

FDO1
Protein FDO1

1

0

High-throughput

0.460

High

755247

NUP82
Nucleoporin NUP82

1

0

High-throughput

0.460

High

755251

MET28
Transcriptional activator of sulfur metabolism MET28

1

0

High-throughput

0.460

High

755265

TEA1
TY1 enhancer activator

1

0

High-throughput

0.460

High

755272

MPS2
Monopolar spindle protein 2

1

0

High-throughput

0.460

High

755283

CIK1
Spindle pole body-associated protein CIK1

1

0

High-throughput

0.460

High

755284

PRS8
26S proteasome regulatory subunit 8 homolog

1

0

High-throughput

0.460

High

755293

LIC4
Protein ATC1/LIC4

1

0

High-throughput

0.460

High

755301

HDA3
HDA1 complex subunit 3

1

0

High-throughput

0.460

High

755306

MFG1
Morphogenetic regulator of filamentous growth protein 1

1

0

High-throughput

0.460

High

755314

SAS10
Something about silencing protein 10

1

0

High-throughput

0.460

High

706681

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

755273

YBP2
YAP1-binding protein 2

1

0

Small-scale

0.458

High

755290

FIN1
Filament protein FIN1

1

0

Small-scale

0.458

High

755303

CENPO
Inner kinetochore subunit MCM21

1

0

Small-scale

0.458

High

755316

RIO1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.458

High

381051

H2B1
Histone H2B.1

1

3

High-throughput

0.445

High

526315

HSP72
Heat shock protein SSA2

1

7

High-throughput

0.445

High

544350

SSB1
Ribosome-associated molecular chaperone SSB1

1

8

High-throughput

0.445

High

735986

SP110
Spindle pole body component 110

1

16

Small-scale

0.445

High

755236

SSZ1
Ribosome-associated complex subunit SSZ1

1

7

High-throughput

0.445

High

755244

SSB2
Ribosome-associated molecular chaperone SSB2

1

8

High-throughput

0.445

High

510357

HSP77
Import motor subunit, mitochondrial

1

9

High-throughput

0.439

High

617383

GBB
Guanine nucleotide-binding protein subunit beta

1

7

High-throughput

0.439

High

736948

CDC3
Cell division control protein 3

1

4

High-throughput

0.439

High

746719

KPR1
Ribose-phosphate pyrophosphokinase 1

1

5

Small-scale

0.439

High

755219

CASP
Protein CASP

1

12

High-throughput

0.439

High

755226

VPP2
V-type proton ATPase subunit a, Golgi isoform

1

2

High-throughput

0.439

High

755227

KPR4
Ribose-phosphate pyrophosphokinase 4

1

5

Small-scale

0.439

High

755231

EXO84
Exocyst complex component EXO84

1

1

High-throughput

0.439

High

755234

KPR3
Ribose-phosphate pyrophosphokinase 3

1

5

Small-scale

0.439

High

755239

SNF7
Vacuolar-sorting protein SNF7

1

3

High-throughput

0.439

High

755243

TSC11
Target of rapamycin complex 2 subunit TSC11

1

1

High-throughput

0.439

High

755246

TBP6
Probable 26S proteasome subunit YTA6

1

2

High-throughput

0.439

High

755248

BNR1
BNI1-related protein 1

1

5

High-throughput

0.439

High

755252

SPR3
Sporulation-regulated protein 3

1

3

High-throughput

0.439

High

755276

YG3A
Uncharacterized protein YGR130C

1

18

High-throughput

0.439

High

755277

AP18B
Clathrin coat assembly protein AP180B

1

2

High-throughput

0.439

High

755296

VPS20
Vacuolar protein sorting-associated protein 20

1

3

High-throughput

0.439

High

755298

GLU2B
Glucosidase 2 subunit beta

1

1

High-throughput

0.439

High

755317

RUD3
GRIP domain-containing protein RUD3

1

18

High-throughput

0.439

High

755319

KPR5
Ribose-phosphate pyrophosphokinase 5

1

5

Small-scale

0.439

High

755321

GYP5
GTPase-activating protein GYP5

1

1

High-throughput

0.439

High

755289

SNU56
56 kDa U1 small nuclear ribonucleoprotein component

1

0

High-throughput

0.438

High

755305

VAM6
Vacuolar morphogenesis protein 6

1

1

High-throughput

0.437

High

743857

YEF3
Uncharacterized protein YEL043W

2

0

High-throughput

0.310

High

755266

SNAPN
Biogenesis of lysosome-related organelles complex 1 subunit SNN1

1

0

High-throughput

0.282

High

550643

SIR4
Regulatory protein SIR4

1

0

High-throughput

0.251

Low

677746

STP22
Suppressor protein STP22 of temperature-sensitive alpha-factor receptor and arginine permease

1

0

High-throughput

0.251

Low

678263

ARE1
Sterol O-acyltransferase 1

1

0

High-throughput

0.251

Low

755053

TIP20
Protein transport protein TIP20

1

0

High-throughput

0.251

Low

755221

YKF0
Uncharacterized protein YKL050C

1

0

High-throughput

0.251

Low

755235

SYSM
Serine--tRNA ligase, mitochondrial

1

0

High-throughput

0.251

Low

755241

VAB2
Biogenesis of lysosome-related organelles complex 1 subunit VAB2

1

0

High-throughput

0.251

Low

755253

FMP32
Protein FMP32, mitochondrial

1

0

High-throughput

0.251

Low

755256

MHP1
MAP-homologous protein 1

1

0

High-throughput

0.251

Low

755259

STB2
Protein STB2

1

0

High-throughput

0.251

Low

755262

YJE9
Uncharacterized protein YJL049W

1

0

High-throughput

0.251

Low

755267

BUL1
Ubiquitin ligase-binding protein BUL1

1

0

High-throughput

0.251

Low

755274

NNF2
Protein NNF2

1

0

High-throughput

0.251

Low

755279

DID2
Vacuolar protein-sorting-associated protein 46

1

0

High-throughput

0.251

Low

755291

VPS64
Vacuolar protein sorting-associated protein 64

1

0

High-throughput

0.251

Low

755295

SHE9
Sensitive to high expression protein 9, mitochondrial

1

0

High-throughput

0.251

Low

755299

HOB2
Protein YPR117W

1

0

High-throughput

0.251

Low

755309

YL031
Putative uncharacterized protein YLR031W

1

0

High-throughput

0.251

Low

755322

MPD2
Protein disulfide isomerase MPD2

1

0

High-throughput

0.251

Low

755308

UBR2
E3 ubiquitin-protein ligase UBR2

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025