HitPredict

Interactor 1: IF4F1 (P39935)
Eukaryotic initiation factor 4F subunit p150 (eIF-4F p150) (eIF4F p150) (Translation initiation factor 4(4)-F(6) subunit gamma(3) protein 1) (eIF4G1) (mRNA cap-binding protein complex subunit p150)
Gene: TIF4631

Interactor 2: SSB2 (P40150)
Ribosome-associated molecular chaperone SSB2 (EC 3.6.4.10) (Heat shock protein SSB2) (Hsp70 chaperone Ssb)
Gene: SSB2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	26777405, 16429126
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0010494 - cytoplasmic stress granule
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 952 Sc			1 613
+	Sc
		511406 IF4F1_YEAST (1-952): 0: 555: 100.00		SSB1_YEAST (1-613): 0: 1118: 99.35
+	Sc
		511407 IF4F2_YEAST (1-952): 2.02e-170: 522: 48.16		SSB1_YEAST (1-613): 0: 1118: 99.35
+	Hs
		503878 IF4G2_HUMAN (551-949): 2.64e-104: 347: 22.93		HSP7C_HUMAN (5-612): 0: 897: 60.00
+	Hs
		203334 IF4G3_HUMAN (2-904): 1.93e-97: 338: 17.58		HSP7C_HUMAN (5-612): 0: 897: 60.00
+	Sc
		450055 IF4F1_YEAST (1-952): 0: 555: 100.00		HSP73_YEAST (9-611): 0: 677: 60.66
+	Hs
		203342 IF4G3_HUMAN (2-904): 1.93e-97: 338: 17.58		HS71L_HUMAN (5-612): 0: 893: 59.51
+	Hs
		504727 PAIP1_HUMAN (481-851): 1.17e-58: 210: 16.54		HSP7C_HUMAN (5-612): 0: 897: 60.00
+	Hs
		504356 NAV3_HUMAN (9-566): 8.92e-39: 159: 12.35		HSP7C_HUMAN (5-612): 0: 897: 60.00
+	Hs
		503940 IF4G1_HUMAN (5-544): 1.08e-09: 64.9: 9.06		HSP7C_HUMAN (5-612): 0: 897: 60.00