Interactor 1: VHL (P40337)
von Hippel-Lindau disease tumor suppressor (Protein G7) (pVHL)
Gene: VHL

Interactor 2: TBK1 (Q9UHD2)
Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase 1)
Gene: TBK1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.52 0.60 0.561

The method score is based on:

Property Details
Experiments 31810986
Identification Methods pull down, affinity chromatography technology, unspecified method
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0010629 - negative regulation of gene expression
GO:1904262 - negative regulation of TORC1 signaling
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 213
Hs

1 729
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024