HitPredict

Interactor 1: YPT52 (P36018)
GTP-binding protein YPT52
Gene: YPT52

Interactor 2: VAM6 (Q07468)
Vacuolar morphogenesis protein 6 (Vacuolar protein sorting-associated protein 39)
Gene: VAM6

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	21325627
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000329 - fungal-type vacuole membrane GO:0006886 - intracellular protein transport
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 234 Sc			1 1049
+	Sc
		779640 VPS21_YEAST (5-232): 5.99e-57: 181: 48.25		VAM6_YEAST (1-1049): 0: 1498: 100.00
+	Hs
		900948 RAB5C_HUMAN (3-234): 4.3e-79: 238: 46.55		TGFA1_HUMAN (575-1029): 6.19e-81: 284: 19.19
+	Dm
		1463780 RAB5_DROME (3-233): 1.84e-59: 188: 50.22		VPS8_DROME (504-1040): 1.09e-91: 320: 13.37
+	Hs
		1356524 RAB2B_HUMAN (4-233): 7.96e-72: 219: 28.87		TGFA1_HUMAN (575-1029): 6.19e-81: 284: 19.19
+	Hs
		976553 RB11A_HUMAN (4-233): 1.58e-72: 221: 33.77		VPS11_HUMAN (605-1031): 4.33e-77: 274: 14.22
+	Hs
		976623 RB11A_HUMAN (4-233): 1.58e-72: 221: 33.77		VPS18_HUMAN (547-1017): 2.64e-68: 249: 13.35
+	Hs
		631466 RAB5A_HUMAN (3-234): 3.64e-56: 179: 46.35		VPS11_HUMAN (605-1031): 4.33e-77: 274: 14.22
+	Sc
		698101 YPT52_YEAST (1-234): 9.89e-76: 230: 100.00		PEP3_YEAST (628-1037): 3.83e-56: 212: 13.40
+	Hs
		631526 RAB5A_HUMAN (3-234): 3.64e-56: 179: 46.35		VPS18_HUMAN (547-1017): 2.64e-68: 249: 13.35
+	Sc
		661745 YPT52_YEAST (1-234): 9.89e-76: 230: 100.00		VPS3_YEAST (544-967): 2.46e-51: 198: 14.32
+	Dm
		1173482 RAB5_DROME (3-233): 1.84e-59: 188: 50.22		VPS18_DROME (574-1042): 3.98e-64: 237: 14.68
+	Sc
		779649 YPT52_YEAST (1-234): 9.89e-76: 230: 100.00		VPS41_YEAST (643-984): 1.08e-37: 155: 12.61
+	Sc
		661744 VPS21_YEAST (5-232): 5.99e-57: 181: 48.25		VPS3_YEAST (544-967): 2.46e-51: 198: 14.32
+	Hs
		900916 RAB5C_HUMAN (3-234): 4.3e-79: 238: 46.55		VPS8_HUMAN (502-1021): 1.6e-13: 77.5: 11.05
+	Sc
		779650 YPT52_YEAST (1-234): 9.89e-76: 230: 100.00		VPS8_YEAST (619-1035): 9.5e-13: 74.9: 13.82
+	Hs
		976409 RB11A_HUMAN (4-233): 1.58e-72: 221: 33.77		VPS8_HUMAN (502-1021): 1.6e-13: 77.5: 11.05
+	Hs
		631338 RAB5A_HUMAN (3-234): 3.64e-56: 179: 46.35		VPS8_HUMAN (502-1021): 1.6e-13: 77.5: 11.05
+	Sc
		779608 VPS21_YEAST (5-232): 5.99e-57: 181: 48.25		VPS8_YEAST (619-1035): 9.5e-13: 74.9: 13.82
+	Sc
		779679 YPT53_YEAST (2-193): 3.19e-54: 175: 53.13		VPS8_YEAST (619-1035): 9.5e-13: 74.9: 13.82