Protein: VPS8
Vacuolar protein sorting-associated protein 8 (Vacuolar protein-targeting protein 8)

Gene: VPS8
Organism: Saccharomyces cerevisiae S288C
Interactions: 35
UniProt ID: P39702

Gene Ontology (top 5):
GO:0005770 - late endosome
GO:0005795 - Golgi stack
GO:0006623 - protein targeting to vacuole
GO:0008270 - zinc ion binding
GO:0016020 - membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

556606

PEP5
E3 ubiquitin-protein ligase PEP5

9

1

Small-scale

0.752

High

698109

PEP3
Vacuolar membrane protein PEP3

7

8

Small-scale

0.750

High

635039

VPS33
Vacuolar protein sorting-associated protein 33

8

2

Small-scale

0.746

High

813580

VPS16
Vacuolar protein sorting-associated protein 16

7

2

Small-scale

0.742

High

779608

VPS21
Vacuolar protein sorting-associated protein 21

7

6

Small-scale

0.741

High

661751

VPS3
Vacuolar protein sorting-associated protein 3

7

0

Small-scale

0.706

High

813582

VAM6
Vacuolar morphogenesis protein 6

4

7

Small-scale

0.677

High

779650

YPT52
GTP-binding protein YPT52

2

6

Small-scale

0.584

High

813583

HSP42
Heat shock protein 42

2

1

High-throughput

0.533

High

524000

HSP71
Heat shock protein SSA1

2

1

High-throughput

0.504

High

544934

SSB1
Ribosome-associated molecular chaperone SSB1

2

1

High-throughput

0.504

High

649828

VPS34
Phosphatidylinositol 3-kinase VPS34

1

0

Small-scale

0.493

High

779679

YPT53
GTP-binding protein YPT53

1

6

Small-scale

0.481

High

808247

VPS41
Vacuolar protein sorting-associated protein 41

1

2

High-throughput

0.479

High

707144

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

746135

PEP12
Syntaxin PEP12

1

1

Small-scale

0.457

High

743388

TOR2
Serine/threonine-protein kinase TOR2

1

1

High-throughput

0.437

High

392757

HSP82
ATP-dependent molecular chaperone HSP82

1

1

High-throughput

0.407

High

526737

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.407

High

579418

HSC82
ATP-dependent molecular chaperone HSC82

1

1

High-throughput

0.407

High

741611

HSP7F
Heat shock protein homolog SSE1

1

3

High-throughput

0.407

High

742854

HSP79
Heat shock protein homolog SSE2

1

3

High-throughput

0.407

High

813577

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.407

High

575342

EI2BA
Translation initiation factor eIF2B subunit alpha

1

0

High-throughput

0.279

Low

721948

XPO1
Exportin-1

1

0

High-throughput

0.279

Low

780149

SDS22
Protein phosphatase 1 regulatory subunit SDS22

1

0

High-throughput

0.279

Low

748217

VAM7
Vacuolar morphogenesis protein 7

1

0

Small-scale

0.261

Low

405093

LEU3
3-isopropylmalate dehydrogenase

1

0

High-throughput

0.261

Low

644784

CLH
Clathrin heavy chain

1

0

High-throughput

0.261

Low

506459

U5072
UPF0507 protein YML002W

1

0

Small-scale

0.251

Low

813581

VPS38
Vacuolar protein sorting-associated protein 38

1

0

Small-scale

0.251

Low

670730

SIS1
Protein SIS1

1

0

High-throughput

0.232

Low

752277

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.232

Low

813578

TCPE
T-complex protein 1 subunit epsilon

1

0

High-throughput

0.232

Low

813579

DPH4
Diphthamide biosynthesis protein 4

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025