HitPredict

Interactor 1: SWD2 (P36104)
COMPASS component SWD2 (Complex proteins associated with SET1 protein SWD2) (Set1C component SWD2)
Gene: SWD2

Interactor 2: BRE1 (Q07457)
E3 ubiquitin-protein ligase BRE1 (EC 2.3.2.27) (Brefeldin A-sensitivity protein 1) (RING-type E3 ubiquitin transferase BRE1)
Gene: BRE1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	18849979
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000781 - chromosome, telomeric region GO:0005634 - nucleus GO:0031509 - subtelomeric heterochromatin formation
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 329 Sc			1 700
+	Hs
		1380296 FBXW7_HUMAN (2-273): 1.38e-64: 218: 13.97		MRCKB_HUMAN (67-632): 2.5e-38: 155: 12.56
+	Hs
		1365564 FBXW7_HUMAN (2-273): 1.38e-64: 218: 13.97		MY18A_HUMAN (76-573): 1.46e-13: 77: 10.67
+	Hs
		773243 FBXW7_HUMAN (2-273): 1.38e-64: 218: 13.97		MYH10_HUMAN (10-357): 1.7e-12: 73.2: 8.26
+	Hs
		772944 FBXW7_HUMAN (2-273): 1.38e-64: 218: 13.97		MYH9_HUMAN (1-311): 9.55e-09: 61.2: 8.68
+	Hs
		1334181 POC1A_HUMAN (146-329): 3.66e-35: 133: 14.67		MYO5C_HUMAN (138-650): 1.29e-26: 118: 12.76
+	Hs
		587585 LIS1_HUMAN (2-184): 6.08e-53: 181: 11.82		DESP_HUMAN (127-645): 9.9e-10: 64.2: 14.61
+	Hs
		776833 POC1A_HUMAN (146-329): 3.66e-35: 133: 14.67		MYH11_HUMAN (4-552): 9.83e-20: 96.9: 10.57
+	Hs
		587723 WDR5B_HUMAN (146-328): 8.77e-44: 154: 14.21		DESP_HUMAN (127-645): 9.9e-10: 64.2: 14.61
+	Hs
		156715 PRP4_HUMAN (115-328): 1.78e-39: 147: 11.21		CTRO_HUMAN (149-643): 9.62e-11: 67.7: 14.74
+	Hs
		209283 PRP4_HUMAN (115-328): 1.78e-39: 147: 11.21		FKB15_HUMAN (409-647): 6.06e-10: 65: 14.34
+	Hs
		272639 GBB2_HUMAN (18-141): 4.96e-11: 64.8: 17.32		BRE1B_HUMAN (315-700): 1.64e-34: 143: 20.73
+	Hs
		965122 WDR5_HUMAN (193-328): 4.51e-32: 124: 17.65		MY18A_HUMAN (76-573): 1.46e-13: 77: 10.67
+	Hs
		1211892 POC1A_HUMAN (146-329): 3.66e-35: 133: 14.67		FKB15_HUMAN (409-647): 6.06e-10: 65: 14.34
+	Hs
		157718 SNR40_HUMAN (141-329): 6.94e-34: 129: 13.61		CTRO_HUMAN (149-643): 9.62e-11: 67.7: 14.74
+	Hs
		587823 NLE1_HUMAN (191-328): 8.63e-33: 128: 17.48		DESP_HUMAN (127-645): 9.9e-10: 64.2: 14.61
+	Hs
		157170 WDR5_HUMAN (193-328): 4.51e-32: 124: 17.65		CTRO_HUMAN (149-643): 9.62e-11: 67.7: 14.74
+	Hs
		587609 WDR5_HUMAN (193-328): 4.51e-32: 124: 17.65		DESP_HUMAN (127-645): 9.9e-10: 64.2: 14.61
+	Hs
		587704 WDR82_HUMAN (56-328): 1.76e-30: 118: 12.41		DESP_HUMAN (127-645): 9.9e-10: 64.2: 14.61
+	Hs
		157418 TAF5_HUMAN (10-221): 7.72e-27: 112: 14.88		CTRO_HUMAN (149-643): 9.62e-11: 67.7: 14.74
+	Hs
		157870 GBB4_HUMAN (18-141): 1.14e-11: 66.8: 18.11		CTRO_HUMAN (149-643): 9.62e-11: 67.7: 14.74