HitPredict

Interactor 1: HNF4A (P41235)
Hepatocyte nuclear factor 4-alpha (HNF-4-alpha) (Nuclear receptor subfamily 2 group A member 1) (Transcription factor 14) (TCF-14) (Transcription factor HNF-4)
Gene: HNF4A

Interactor 2: PABP4 (Q13310)
Polyadenylate-binding protein 4 (PABP-4) (Poly(A)-binding protein 4) (Activated-platelet protein 1) (APP-1) (Inducible poly(A)-binding protein) (iPABP)
Gene: PABPC4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	17353931
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0007596 - blood coagulation
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 474 Hs			1 644
+	Hs
		369534 ESR1_HUMAN (10-432): 3.46e-112: 345: 21.37		PABP4_HUMAN (1-644): 0: 585: 100.00
+	Hs
		1031409 ESR2_HUMAN (44-374): 2.23e-99: 310: 27.64		PABP4_HUMAN (1-644): 0: 585: 100.00
+	Hs
		611434 NR4A1_HUMAN (11-380): 1.23e-98: 310: 25.00		PABP4_HUMAN (1-644): 0: 585: 100.00
+	Hs
		368886 ESR1_HUMAN (10-432): 3.46e-112: 345: 21.37		PABP1_HUMAN (1-644): 0: 542: 74.54
+	Mm
		509289 RARA_MOUSE (9-387): 1.6e-107: 328: 25.00		PABP1_MOUSE (1-644): 0: 542: 74.69
+	Hs
		370422 ESR1_HUMAN (10-432): 3.46e-112: 345: 21.37		PABP3_HUMAN (1-644): 7.04e-175: 513: 68.98
+	Hs
		516359 NR4A1_HUMAN (11-380): 1.23e-98: 310: 25.00		PABP1_HUMAN (1-644): 0: 542: 74.54
+	Hs
		369739 ESR1_HUMAN (10-432): 3.46e-112: 345: 21.37		PAP1L_HUMAN (1-636): 6.79e-165: 487: 63.89
+	Hs
		1269600 ESR2_HUMAN (44-374): 2.23e-99: 310: 27.64		PABP3_HUMAN (1-644): 7.04e-175: 513: 68.98
+	Hs
		1119140 ESR2_HUMAN (44-374): 2.23e-99: 310: 27.64		PAP1L_HUMAN (1-636): 6.79e-165: 487: 63.89
+	Hs
		368961 ESR1_HUMAN (10-432): 3.46e-112: 345: 21.37		NUCL_HUMAN (2-89): 1.4e-20: 98.4: 31.82
+	Hs
		370176 ESR1_HUMAN (10-432): 3.46e-112: 345: 21.37		PABP5_HUMAN (4-93): 1.22e-15: 81: 23.33
+	Hs
		369064 ESR1_HUMAN (10-432): 3.46e-112: 345: 21.37		TIA1_HUMAN (4-109): 7.62e-12: 69.5: 24.53
+	Hs
		582413 ESR2_HUMAN (44-374): 2.23e-99: 310: 27.64		NUCL_HUMAN (2-89): 1.4e-20: 98.4: 31.82
+	Hs
		1269332 ESR2_HUMAN (44-374): 2.23e-99: 310: 27.64		PABP5_HUMAN (4-93): 1.22e-15: 81: 23.33
+	Hs
		680471 ESR2_HUMAN (44-374): 2.23e-99: 310: 27.64		TIA1_HUMAN (4-109): 7.62e-12: 69.5: 24.53