Protein: NU133
Nuclear pore complex protein Nup133 (133 kDa nucleoporin) (Nucleoporin Nup133)

Gene: NU133, NUP133
Organism: Homo sapiens
Interactions: 176
UniProt ID: Q8WUM0

Gene Ontology (top 5):
GO:0000776 - kinetochore
GO:0000972 - transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery
GO:0005635 - nuclear envelope
GO:0005643 - nuclear pore
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

945283

NU107
Nuclear pore complex protein Nup107

14

5

Small-scale

0.984

High

1338862

NUP43
Nucleoporin Nup43

8

1

Small-scale

0.748

High

916006

NUP98
Nuclear pore complex protein Nup98-Nup96

6

11

Small-scale

0.732

High

938250

SEC13
Protein SEC13 homolog

5

4

Small-scale

0.718

High

1356932

NUP85
Nuclear pore complex protein Nup85

5

1

Small-scale

0.706

High

386017

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

5

2

High-throughput

0.702

High

1356921

SEH1
Nucleoporin SEH1

3

4

Small-scale

0.667

High

1339084

NUP37
Nucleoporin Nup37

4

0

Small-scale

0.664

High

890373

NU153
Nuclear pore complex protein Nup153

3

9

Small-scale

0.650

High

1356948

SPAST
Spastin

3

0

High-throughput

0.634

High

291457

NU155
Nuclear pore complex protein Nup155

1

2

High-throughput

0.618

High

1356912

ELYS
Protein ELYS

3

0

Small-scale

0.613

High

173133

XPO1
Exportin-1

2

2

Small-scale

0.611

High

1209436

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

3

0

High-throughput

0.606

High

1251094

TPTE2
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2

2

0

High-throughput

0.585

High

1356950

ZRAN1
Ubiquitin thioesterase ZRANB1

2

2

High-throughput

0.584

High

1356951

NUP50
Nuclear pore complex protein Nup50

2

3

High-throughput

0.584

High

1085258

NU160
Nuclear pore complex protein Nup160

2

0

Small-scale

0.576

High

1356949

NXF1
Nuclear RNA export factor 1

2

1

Small-scale

0.571

High

837744

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

2

0

High-throughput

0.559

High

951298

SC61B
Protein transport protein Sec61 subunit beta

2

0

High-throughput

0.559

High

1040861

MECOM
Histone-lysine N-methyltransferase MECOM

2

0

High-throughput

0.559

High

1356846

PTPM1
Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1

2

2

High-throughput

0.558

High

483167

CLCA
Clathrin light chain A

1

1

High-throughput

0.536

High

483374

CLCB
Clathrin light chain B

1

1

High-throughput

0.536

High

721043

CLIP1
CAP-Gly domain-containing linker protein 1

1

1

High-throughput

0.536

High

849387

RANG
Ran-specific GTPase-activating protein

1

3

High-throughput

0.536

High

981609

RAN
GTP-binding nuclear protein Ran

1

1

High-throughput

0.536

High

1134302

IMB1
Importin subunit beta-1

1

1

High-throughput

0.536

High

1134658

NUMA1
Nuclear mitotic apparatus protein 1

1

2

High-throughput

0.536

High

1356934

FOXP3
Forkhead box protein P3

1

1

High-throughput

0.536

High

185102

TELT
Telethonin

1

0

High-throughput

0.518

High

1119220

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

0

High-throughput

0.518

High

474854

VIME
Vimentin

1

0

High-throughput

0.513

High

549205

CDK4
Cyclin-dependent kinase 4

1

0

High-throughput

0.513

High

891263

GSK3A
Glycogen synthase kinase-3 alpha

1

0

High-throughput

0.513

High

976448

RB11A
Ras-related protein Rab-11A

1

0

High-throughput

0.513

High

1100920

G3BP1
Ras GTPase-activating protein-binding protein 1

1

0

High-throughput

0.513

High

1152170

MARE1
Microtubule-associated protein RP/EB family member 1

1

0

High-throughput

0.513

High

1163088

H2B2E
Histone H2B type 2-E

1

0

High-throughput

0.513

High

1291641

CMTD1
Catechol O-methyltransferase domain-containing protein 1

1

0

High-throughput

0.513

High

1356956

TN13B
Tumor necrosis factor ligand superfamily member 13B

1

0

High-throughput

0.513

High

883924

CENPF
Centromere protein F

1

2

Small-scale

0.506

High

831125

CCNF
Cyclin-F

1

0

High-throughput

0.493

High

1091323

FOXL1
Forkhead box protein L1

1

1

High-throughput

0.489

High

1142115

P2RY6
P2Y purinoceptor 6

1

1

High-throughput

0.489

High

1253571

FOXI2
Forkhead box protein I2

1

1

High-throughput

0.489

High

1356935

FOXQ1
Forkhead box protein Q1

1

2

High-throughput

0.489

High

157660

CTRO
Citron Rho-interacting kinase

1

1

High-throughput

0.479

High

285380

EED
Polycomb protein EED

1

1

High-throughput

0.479

High

625522

CSK22
Casein kinase II subunit alpha'

1

2

High-throughput

0.479

High

634549

LMNB1
Lamin-B1

1

2

High-throughput

0.479

High

731500

STIP1
Stress-induced-phosphoprotein 1

1

2

High-throughput

0.479

High

775581

NU214
Nuclear pore complex protein Nup214

1

5

Small-scale

0.479

High

980042

H4
Histone H4

1

1

High-throughput

0.479

High

997888

CSK21
Casein kinase II subunit alpha

1

2

High-throughput

0.479

High

1052841

DUSP2
Dual specificity protein phosphatase 2

1

1

High-throughput

0.479

High

1058549

CKAP4
Cytoskeleton-associated protein 4

1

2

High-throughput

0.479

High

1125570

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

2

High-throughput

0.479

High

1141821

EEA1
Early endosome antigen 1

1

1

High-throughput

0.479

High

1199342

GLE1
mRNA export factor GLE1

1

2

High-throughput

0.479

High

1228442

FTM
Protein fantom

1

1

High-throughput

0.479

High

1312201

MIRO2
Mitochondrial Rho GTPase 2

1

1

High-throughput

0.479

High

1329767

SIR6
NAD-dependent protein deacylase sirtuin-6

1

1

High-throughput

0.479

High

1337820

CSK23
Casein kinase II subunit alpha 3

1

2

High-throughput

0.479

High

1356919

CHM4C
Charged multivesicular body protein 4c

1

1

High-throughput

0.479

High

1356922

P121A
Nuclear envelope pore membrane protein POM 121

1

4

High-throughput

0.479

High

1356940

SENP2
Sentrin-specific protease 2

1

1

High-throughput

0.479

High

125540

LEG9
Galectin-9

1

0

High-throughput

0.458

High

129279

MEN1
Menin

1

0

High-throughput

0.458

High

223210

PRC1
Protein regulator of cytokinesis 1

1

0

High-throughput

0.458

High

242400

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

272342

OBSL1
Obscurin-like protein 1

1

0

High-throughput

0.458

High

401203

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

414292

P53
Cellular tumor antigen p53

1

0

High-throughput

0.458

High

508335

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

0

High-throughput

0.458

High

611251

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

0

High-throughput

0.458

High

698938

CALX
Calnexin

1

0

High-throughput

0.458

High

832929

CETN2
Centrin-2

1

0

Small-scale

0.458

High

884370

UBE2A
Ubiquitin-conjugating enzyme E2 A

1

0

High-throughput

0.458

High

890545

RBP2
E3 SUMO-protein ligase RanBP2

1

0

High-throughput

0.458

High

894932

EMD
Emerin

1

0

High-throughput

0.458

High

1087216

STX4
Syntaxin-4

1

0

High-throughput

0.458

High

1097711

STK3
Serine/threonine-protein kinase 3

1

0

Small-scale

0.458

High

1107053

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.458

High

1113828

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1136663

HERP1
Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein

1

0

High-throughput

0.458

High

1140609

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

1161570

IF16
Gamma-interferon-inducible protein 16

1

0

High-throughput

0.458

High

1178278

CL16A
Protein CLEC16A

1

0

High-throughput

0.458

High

1229007

RNF43
E3 ubiquitin-protein ligase RNF43

1

0

High-throughput

0.458

High

1229585

VIR
Protein virilizer homolog

1

0

High-throughput

0.458

High

1252151

SYNE3
Nesprin-3

1

0

High-throughput

0.458

High

1280361

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

0

High-throughput

0.458

High

1281568

SLN11
Schlafen family member 11

1

0

High-throughput

0.458

High

1288543

ZN598
E3 ubiquitin-protein ligase ZNF598

1

0

High-throughput

0.458

High

1289253

DTX2
Probable E3 ubiquitin-protein ligase DTX2

1

0

High-throughput

0.458

High

1289484

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

1292728

TRI69
E3 ubiquitin-protein ligase TRIM69

1

0

Small-scale

0.458

High

1311944

SKA3
Spindle and kinetochore-associated protein 3

1

0

Small-scale

0.458

High

1339105

NUP35
Nucleoporin NUP35

1

0

High-throughput

0.458

High

1356913

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

0

High-throughput

0.458

High

1356915

LRC59
Leucine-rich repeat-containing protein 59

1

0

High-throughput

0.458

High

1356918

DCPS
m7GpppX diphosphatase

1

0

High-throughput

0.458

High

1356923

DNJC1
DnaJ homolog subfamily C member 1

1

0

High-throughput

0.458

High

1356924

CI072
Guanine nucleotide exchange factor C9orf72

1

0

High-throughput

0.458

High

1356925

ZN363
RING finger and CHY zinc finger domain-containing protein 1

1

0

High-throughput

0.458

High

1356926

SEC62
Translocation protein SEC62

1

0

High-throughput

0.458

High

1356929

B9D2
B9 domain-containing protein 2

1

0

High-throughput

0.458

High

1356930

DERL1
Derlin-1

1

0

High-throughput

0.458

High

1356933

ACE2
Angiotensin-converting enzyme 2

1

0

High-throughput

0.458

High

1356939

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1356941

ANLN
Anillin

1

0

High-throughput

0.458

High

1356943

FBX6
F-box only protein 6

1

0

High-throughput

0.458

High

1356946

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

1356947

WWOX
WW domain-containing oxidoreductase

1

0

High-throughput

0.458

High

1007740

RAE1L
mRNA export factor RAE1

1

2

Small-scale

0.457

High

1276136

NUP54
Nucleoporin p54

1

9

Small-scale

0.457

High

171529

S27A2
Long-chain fatty acid transport protein 2

1

2

High-throughput

0.445

High

1240910

S27A4
Long-chain fatty acid transport protein 4

1

2

High-throughput

0.445

High

1243635

S27A1
Long-chain fatty acid transport protein 1

1

2

High-throughput

0.445

High

1356944

AAAS
Aladin

1

0

Small-scale

0.438

High

331185

KI20A
Kinesin-like protein KIF20A

1

1

High-throughput

0.437

High

412319

NTRK1
High affinity nerve growth factor receptor

1

1

High-throughput

0.437

High

1356927

RING2
E3 ubiquitin-protein ligase RING2

1

1

High-throughput

0.437

High

1356931

DUS26
Dual specificity protein phosphatase 26

1

1

High-throughput

0.437

High

1356942

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

1

High-throughput

0.437

High

1356953

ALK
ALK tyrosine kinase receptor

1

1

High-throughput

0.437

High

911643

NCBP2
Nuclear cap-binding protein subunit 2

1

0

High-throughput

0.426

High

1309392

SPNS2
Sphingosine-1-phosphate transporter SPNS2

1

0

High-throughput

0.426

High

1330720

SIGL1
SIGLEC family-like protein 1

1

0

High-throughput

0.426

High

1356917

S67A1
Solute carrier family 67 member A1

1

0

High-throughput

0.426

High

1356945

GTR9
Solute carrier family 2, facilitated glucose transporter member 9

1

0

High-throughput

0.426

High

1356955

XCT
Cystine/glutamate transporter

1

0

High-throughput

0.426

High

1101606

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

1

High-throughput

0.407

High

372677

MYC
Myc proto-oncogene protein

3

0

High-throughput

0.342

High

749243

CD70
CD70 antigen

1

0

High-throughput

0.279

Low

939514

FCGRN
IgG receptor FcRn large subunit p51

1

0

High-throughput

0.279

Low

1341274

COQ8A
Atypical kinase COQ8A, mitochondrial

1

0

High-throughput

0.279

Low

1356920

HDA11
Histone deacetylase 11

1

0

High-throughput

0.279

Low

1356936

UN93B
Protein unc-93 homolog B1

1

0

High-throughput

0.279

Low

1356957

PUS1
Pseudouridylate synthase 1 homolog

1

0

High-throughput

0.279

Low

1356958

RPKL1
Ribosomal protein S6 kinase-like 1

1

0

High-throughput

0.279

Low

521833

H14
Histone H1.4

1

0

High-throughput

0.269

Low

248013

NUPR1
Nuclear protein 1

1

0

High-throughput

0.249

Low

260209

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.249

Low

519175

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

0

High-throughput

0.249

Low

606937

CEBPB
CCAAT/enhancer-binding protein beta

1

0

High-throughput

0.249

Low

613110

EGR1
Early growth response protein 1

1

0

High-throughput

0.249

Low

768735

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

799326

BRCA1
Breast cancer type 1 susceptibility protein

1

0

High-throughput

0.249

Low

851793

NKX21
Homeobox protein Nkx-2.1

1

0

High-throughput

0.249

Low

1100165

TIF1B
Transcription intermediary factor 1-beta

1

0

High-throughput

0.249

Low

1111623

STIM1
Stromal interaction molecule 1

1

0

High-throughput

0.249

Low

1135749

HAPR1
HUWE1-associated protein modifying stress responses 1

1

0

High-throughput

0.249

Low

1137417

SUZ12
Polycomb protein SUZ12

1

0

High-throughput

0.249

Low

1147647

TOM20
Mitochondrial import receptor subunit TOM20 homolog

1

0

High-throughput

0.249

Low

1156794

E2F4
Transcription factor E2F4

1

0

High-throughput

0.249

Low

1249053

LMBRL
Protein LMBR1L

1

0

High-throughput

0.249

Low

1254804

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1276536

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.249

Low

1352652

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.249

Low

1356914

ESR2
Estrogen receptor beta

1

0

High-throughput

0.249

Low

1356916

VP33A
Vacuolar protein sorting-associated protein 33A

1

0

High-throughput

0.249

Low

1356937

Q9H4D1
Receptor-interacting serine/threonine-protein kinase 4

1

0

High-throughput

0.249

Low

1356938

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

1356952

HECD1
E3 ubiquitin-protein ligase HECTD1

1

0

High-throughput

0.249

Low

1356954

RL26L
Ribosomal protein uL24-like

1

0

High-throughput

0.249

Low

1087

SIM26
Small integral membrane protein 26

1

0

High-throughput

0.232

Low

166364

ZNT4
Probable proton-coupled zinc antiporter SLC30A4

1

0

High-throughput

0.232

Low

653460

HEMH
Ferrochelatase, mitochondrial

1

0

High-throughput

0.232

Low

683295

TNR5
Tumor necrosis factor receptor superfamily member 5

1

0

High-throughput

0.232

Low

1279066

RIC3
Protein RIC-3

1

0

High-throughput

0.232

Low

1334387

UXS1
UDP-glucuronic acid decarboxylase 1

1

0

High-throughput

0.232

Low

1335646

MOT11
Monocarboxylate transporter 11

1

0

High-throughput

0.232

Low

1356928

S1PR3
Sphingosine 1-phosphate receptor 3

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025