HitPredict

Interactor 1: TNR3 (P36941)
Tumor necrosis factor receptor superfamily member 3 (Lymphotoxin-beta receptor) (Tumor necrosis factor C receptor) (Tumor necrosis factor receptor 2-related protein) (Tumor necrosis factor receptor type III) (TNF-RIII) (TNFR-III)
Gene: LTBR

Interactor 2: RN114 (Q9Y508)
E3 ubiquitin-protein ligase RNF114 (EC 2.3.2.27) (RING finger protein 114) (RING-type E3 ubiquitin transferase RNF114) (Zinc finger protein 228) (Zinc finger protein 313)
Gene: RNF114

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 435 Hs			1 228
+	Hs
		787572 TNR3_HUMAN (1-435): 5.83e-134: 393: 100.00		RN166_HUMAN (2-227): 3.3e-58: 185: 40.69
+	Hs
		787583 TNR3_HUMAN (1-435): 5.83e-134: 393: 100.00		TRIM4_HUMAN (18-163): 1.06e-27: 111: 20.13
+	Hs
		136666 TNR3_HUMAN (1-435): 5.83e-134: 393: 100.00		TRAF5_HUMAN (21-174): 3.56e-26: 107: 20.25
+	Hs
		787558 TNR3_HUMAN (1-435): 5.83e-134: 393: 100.00		TRI68_HUMAN (14-130): 1.5e-23: 99: 14.60
+	Mm
		894452 TNR3_MOUSE (1-419): 1.57e-105: 320: 68.17		TRAF5_MOUSE (21-174): 1.56e-26: 108: 21.47
+	Hs
		622645 TNR1A_HUMAN (36-338): 4.37e-53: 185: 22.01		RN138_HUMAN (17-225): 3.46e-49: 163: 31.09
+	Hs
		622718 TNR1A_HUMAN (36-338): 4.37e-53: 185: 22.01		TRAF6_HUMAN (19-179): 7.75e-28: 111: 20.48
+	Mm
		204647 TNR11_MOUSE (4-254): 3.02e-49: 178: 28.74		TRAF6_MOUSE (19-179): 8.23e-29: 114: 19.88
+	Hs
		683378 TNR5_HUMAN (15-287): 6.78e-52: 177: 26.01		TRAF6_HUMAN (19-179): 7.75e-28: 111: 20.48
+	Mm
		204646 TNR11_MOUSE (4-254): 3.02e-49: 178: 28.74		TRAF5_MOUSE (21-174): 1.56e-26: 108: 21.47
+	Hs
		136662 TNR5_HUMAN (15-287): 6.78e-52: 177: 26.01		TRAF5_HUMAN (21-174): 3.56e-26: 107: 20.25
+	Mm
		693159 TNR5_MOUSE (15-286): 8.37e-49: 169: 23.16		TRAF6_MOUSE (19-179): 8.23e-29: 114: 19.88
+	Mm
		999859 TNR27_MOUSE (45-367): 1.36e-47: 167: 15.84		TRAF6_MOUSE (19-179): 8.23e-29: 114: 19.88
+	Mm
		999816 TNR14_MOUSE (4-286): 1.06e-48: 169: 25.52		TRAF5_MOUSE (21-174): 1.56e-26: 108: 21.47
+	Hs
		1437797 TNR27_HUMAN (45-367): 1.74e-46: 163: 19.06		TRAF6_HUMAN (19-179): 7.75e-28: 111: 20.48
+	Hs
		1491435 TNR11_HUMAN (45-254): 9.25e-43: 160: 29.58		TRAF6_HUMAN (19-179): 7.75e-28: 111: 20.48
+	Hs
		623611 TNR11_HUMAN (45-254): 9.25e-43: 160: 29.58		RO52_HUMAN (14-139): 1.06e-27: 111: 19.29
+	Hs
		630385 TNR1B_HUMAN (9-231): 2.58e-43: 159: 30.84		TRAF6_HUMAN (19-179): 7.75e-28: 111: 20.48
+	Hs
		136737 TNR11_HUMAN (45-254): 9.25e-43: 160: 29.58		TRAF5_HUMAN (21-174): 3.56e-26: 107: 20.25
+	Hs
		136714 TNR14_HUMAN (5-287): 1.82e-43: 155: 23.78		TRAF5_HUMAN (21-174): 3.56e-26: 107: 20.25