HitPredict

Interactor 1: NUP62 (P37198)
Nuclear pore glycoprotein p62 (62 kDa nucleoporin) (Nucleoporin Nup62)
Gene: NUP62

Interactor 2: SEC13 (P55735)
Protein SEC13 homolog (GATOR2 complex protein SEC13) (SEC13-like protein 1) (SEC13-related protein)
Gene: SEC13

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.42	0.60	0.506

Property	Details
Experiments	27194810
Identification Methods	two hybrid array, bimolecular fluorescence complementation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005635 - nuclear envelope GO:0005643 - nuclear pore GO:0005654 - nucleoplasm GO:0006606 - protein import into nucleus GO:0006913 - nucleocytoplasmic transport and 1 others more... GO:0051028 - mRNA transport
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 522 Hs			1 322
+	Hs
		319089 SC24D_HUMAN (20-371): 1.72e-27: 119: 11.20		SEC13_HUMAN (1-322): 2.24e-85: 261: 100.00
+	Hs
		789086 NUP62_HUMAN (1-522): 5.23e-77: 253: 100.00		WDR5_HUMAN (2-194): 1.15e-30: 119: 16.67
+	Hs
		925703 SC24C_HUMAN (53-359): 2.54e-22: 103: 11.08		SEC13_HUMAN (1-322): 2.24e-85: 261: 100.00
+	Hs
		915933 NUP98_HUMAN (2-334): 2.52e-13: 75.1: 16.11		SEC13_HUMAN (1-322): 2.24e-85: 261: 100.00
+	Hs
		130546 SPT5H_HUMAN (1-204): 2.35e-14: 78.2: 9.27		POC1A_HUMAN (46-320): 1.8e-60: 200: 18.91
+	Hs
		667395 RPB1_HUMAN (44-233): 7.7e-09: 60.9: 16.75		FBXW7_HUMAN (87-316): 1.16e-41: 155: 14.72
+	Mm
		476218 RPB1_MOUSE (26-230): 5.44e-14: 77.5: 10.70		WDR5_MOUSE (2-194): 1.15e-30: 119: 16.67
+	Hs
		915937 NUP98_HUMAN (2-334): 2.52e-13: 75.1: 16.11		WDR5_HUMAN (2-194): 1.15e-30: 119: 16.67
+	Dm
		1463905 NUP98_DROME (16-342): 4.96e-10: 64.7: 13.14		WDS_DROME (2-198): 7.68e-32: 123: 17.33
+	Sc
		577328 NSP1_YEAST (30-504): 5.03e-29: 123: 16.02		SEH1_YEAST (209-312): 2.36e-09: 59.8: 22.32
+	Sc
		577347 NSP1_YEAST (30-504): 5.03e-29: 123: 16.02		SEC13_YEAST (4-89): 1.88e-09: 59.8: 25.00
+	Hs
		130571 SPT5H_HUMAN (1-204): 2.35e-14: 78.2: 9.27		SNR40_HUMAN (3-131): 2.14e-24: 103: 22.22
+	Sc
		886196 NU145_YEAST (2-463): 5.68e-27: 117: 14.20		SEH1_YEAST (209-312): 2.36e-09: 59.8: 22.32
+	Sc
		886207 NU145_YEAST (2-463): 5.68e-27: 117: 14.20		SEC13_YEAST (4-89): 1.88e-09: 59.8: 25.00
+	Sc
		825167 NU159_YEAST (2-325): 1.44e-17: 88.6: 15.17		SEH1_YEAST (209-312): 2.36e-09: 59.8: 22.32
+	Sc
		825179 NU159_YEAST (2-325): 1.44e-17: 88.6: 15.17		SEC13_YEAST (4-89): 1.88e-09: 59.8: 25.00
+	Sp
		1082632 NU189_SCHPO (2-271): 3.99e-09: 61.6: 17.15		SEH1_SCHPO (100-310): 8.51e-17: 81.6: 16.67
+	Hs
		916022 NUP98_HUMAN (2-334): 2.52e-13: 75.1: 16.11		SEH1_HUMAN (15-180): 1.66e-09: 60.4: 18.75
+	Sp
		313730 NU189_SCHPO (2-271): 3.99e-09: 61.6: 17.15		SEC13_SCHPO (3-147): 1.02e-13: 72.1: 24.85