HitPredict

Interactor 1: MK09 (P45984)
Mitogen-activated protein kinase 9 (MAP kinase 9) (MAPK 9) (EC 2.7.11.24) (JNK-55) (Stress-activated protein kinase 1a) (SAPK1a) (Stress-activated protein kinase JNK2) (c-Jun N-terminal kinase 2)
Gene: MAPK9

Interactor 2: ARRB1 (P49407)
Beta-arrestin-1 (Arrestin beta-1) (Non-visual arrestin-2)
Gene: ARRB1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.86	0.60	0.722

Property	Details
Experiments	32296183, 25416956, 21988832, unassigned1304, 31515488
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 424 Hs			1 418
+	Hs
		827134 MK10_HUMAN (1-424): 1.16e-155: 449: 84.04		ARRB1_HUMAN (1-418): 0: 716: 100.00
+	Hs
		827213 MK14_HUMAN (4-375): 9.3e-130: 379: 48.00		ARRB1_HUMAN (1-418): 0: 716: 100.00
+	Hs
		685833 MK09_HUMAN (1-424): 2.83e-163: 467: 100.00		ARRB2_HUMAN (1-407): 0: 626: 76.15
+	Hs
		685857 MK10_HUMAN (1-424): 1.16e-155: 449: 84.04		ARRB2_HUMAN (1-407): 0: 626: 76.15
+	Rn
		663950 MK10_RAT (1-424): 1.63e-155: 449: 84.04		ARRB2_RAT (1-407): 0: 616: 75.00
+	Hs
		685907 CDK3_HUMAN (23-322): 4.06e-132: 383: 33.01		ARRB2_HUMAN (1-407): 0: 626: 76.15
+	Hs
		658850 MK01_HUMAN (15-364): 1.35e-82: 259: 40.50		ARRB1_HUMAN (1-418): 0: 716: 100.00
+	Hs
		658808 MK01_HUMAN (15-364): 1.35e-82: 259: 40.50		ARRB2_HUMAN (1-407): 0: 626: 76.15