HitPredict

Interactor 1: TAF4 (P47825)
Transcription initiation factor TFIID subunit 4 (110 kDa TBP-associated factor) (Transcription initiation factor TFIID 110 kDa subunit) (TAFII-110) (p110)
Gene: TAF4

Interactor 2: TAF10 (Q9U5W9)
Transcription initiation factor TFIID subunit 10 (Transcription initiation factor TFIID 24 kDa subunit) (TAFII-24) (TAFII24) (dTAF(II)24)
Gene: TAF10

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	11438676, 12482983
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005669 - transcription factor TFIID complex GO:0006367 - transcription initiation at RNA polymerase II promoter GO:0016251 - RNA polymerase II general transcription initiation factor activity
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 921 Dm			1 167
+	Dm
		814203 TAF4_DROME (1-921): 1.76e-95: 323: 100.00		TAFAB_DROME (51-165): 2.6e-48: 154: 53.04
+	Hs
		124203 TAF4_HUMAN (49-921): 1.6e-57: 217: 22.99		TAF10_HUMAN (40-166): 5.98e-53: 169: 51.18
+	At
		137911 TAF4_ARATH (258-919): 6.14e-67: 239: 15.97		TAF10_ARATH (53-166): 5.36e-45: 146: 42.98
+	At
		98810 TAF4B_ARATH (165-918): 4.62e-51: 195: 15.92		TAF10_ARATH (53-166): 5.36e-45: 146: 42.98
+	Sp
		224181 TAF4_SCHPO (603-908): 3.56e-51: 186: 19.41		TAF10_SCHPO (53-166): 1.29e-45: 150: 33.33
+	Sc
		837505 TAF4_YEAST (521-921): 2.61e-34: 137: 16.55		TAF10_YEAST (49-166): 1.46e-42: 142: 22.86
+	Hs
		1021641 SP130_HUMAN (9-711): 2.57e-12: 73.1: 8.75		TAF10_HUMAN (40-166): 5.98e-53: 169: 51.18