HitPredict

Interactor 1: MPK1 (P39745)
Mitogen-activated protein kinase mpk-1 (EC 2.7.11.24) (MAP kinase sur-1)
Gene: mpk-1

Interactor 2: KS6A1 (Q21734)
Putative ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)
Gene: rskn-1

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.48 1.00 0.698

The method score is based on:

Property Details
Experiments 14704431
Identification Methods two hybrid, two hybrid pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase, Pkinase~Pkinase_C
Common GO terms GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0106310 - protein serine kinase activity
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 444
Ce

1 784
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Xl
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025