HitPredict

Interactor 1: SMC2 (P50533)
Structural maintenance of chromosomes protein 2 (SMC protein 2) (SMC-2) (Chromosome assembly protein XCAP-E) (Chromosome-associated protein E)
Gene: SMC2

Interactor 2: CND3L (Q6GN08)
Condensin-2 complex subunit D3-L
Gene: ncapd3.L

Species: Xenopus laevis

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	1.00	0.767

Property	Details
Experiments	14532007, 19915589
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Cnd1~SMC_N
Common GO terms	GO:0005634 - nucleus GO:0051301 - cell division
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1203 Xl			1 1492
+	Hs
		311495 SMC2_HUMAN (1-1194): 1.07e-118: 399: 81.07		CNDD3_HUMAN (20-1492): 0: 1909: 58.10
+	Hs
		789354 SMC4_HUMAN (1-1177): 6.53e-86: 307: 16.27		CNDD3_HUMAN (20-1492): 0: 1909: 58.10
+	Xl
		840137 SMC4_XENLA (1-1175): 1.63e-80: 291: 17.45		CND3L_XENLA (1-1492): 0: 1893: 100.00
+	Ce
		1093621 SMC4_CAEEL (1-1167): 1.76e-100: 352: 17.23		CND_CAEEL (445-1416): 0: 769: 21.39
+	Ce
		999501 MIX1_CAEEL (1-1173): 5.18e-92: 324: 31.41		CND_CAEEL (445-1416): 0: 769: 21.39
+	Hs
		311546 SMC2_HUMAN (1-1194): 1.07e-118: 399: 81.07		CND1_HUMAN (425-1159): 0: 613: 16.77
+	Xl
		840144 SMC2_XENLA (1-1203): 4.86e-124: 414: 100.00		CND1_XENLA (425-1159): 7.11e-169: 546: 15.07
+	Hs
		1063378 SMC4_HUMAN (1-1177): 6.53e-86: 307: 16.27		CND1_HUMAN (425-1159): 0: 613: 16.77
+	Sp
		293952 SMC2_SCHPO (1-1169): 5.25e-101: 349: 36.38		CND1_SCHPO (411-1153): 4.58e-162: 522: 13.74
+	Xl
		840139 SMC4_XENLA (1-1175): 1.63e-80: 291: 17.45		CND1_XENLA (425-1159): 7.11e-169: 546: 15.07
+	Sp
		293953 SMC4_SCHPO (1-1177): 2.74e-85: 305: 17.26		CND1_SCHPO (411-1153): 4.58e-162: 522: 13.74
+	Sc
		758757 SMC2_YEAST (1-1170): 4.06e-91: 321: 35.38		CND1_YEAST (431-1160): 2.91e-149: 488: 14.86
+	Sc
		986208 SMC4_YEAST (1-1173): 8.55e-65: 243: 15.96		CND1_YEAST (431-1160): 2.91e-149: 488: 14.86
+	Ce
		1093623 SMC4_CAEEL (1-1167): 1.76e-100: 352: 17.23		CND1_CAEEL (805-1102): 2.67e-55: 214: 12.75
+	Dm
		1180652 Q7KK96_DROME (1-1178): 1.19e-93: 328: 42.11		Q9VAJ1_DROME (905-1159): 7.06e-58: 222: 15.41
+	Ce
		999503 MIX1_CAEEL (1-1173): 5.18e-92: 324: 31.41		CND1_CAEEL (805-1102): 2.67e-55: 214: 12.75
+	Dm
		1358313 Q9V3A7_DROME (1-1171): 3.63e-87: 312: 15.09		Q9VAJ1_DROME (905-1159): 7.06e-58: 222: 15.41
+	Ce
		823191 DPY27_CAEEL (1-1174): 1.53e-74: 274: 15.66		CND1_CAEEL (805-1102): 2.67e-55: 214: 12.75