HitPredict

Interactor 1: CDK9 (P50750)
Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (C-2K) (Cell division cycle 2-like protein kinase 4) (Cell division protein kinase 9) (Serine/threonine-protein kinase PITALRE) (Tat-associated kinase complex catalytic subunit)
Gene: CDK9

Interactor 2: H2B1A (Q96A08)
Histone H2B type 1-A (Histone H2B, testis) (TSH2B.1) (hTSH2B) (Testis-specific histone H2B)
Gene: H2BC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26209609
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 372 Hs			1 127
+	Hs
		841757 CDK9_HUMAN (1-372): 2.88e-147: 422: 100.00		H2B2E_HUMAN (1-127): 4.39e-54: 167: 85.83
+	Mm
		1208445 CDK9_MOUSE (1-372): 2.88e-146: 420: 98.66		H2B1P_MOUSE (1-127): 2.62e-53: 165: 85.04
+	Hs
		841863 CDK9_HUMAN (1-372): 2.88e-147: 422: 100.00		H2B1L_HUMAN (1-127): 1.35e-52: 163: 85.83
+	Hs
		1026875 MK07_HUMAN (12-372): 2.64e-131: 396: 29.75		H2B1M_HUMAN (1-127): 6.74e-55: 169: 84.25
+	Hs
		1026862 MK07_HUMAN (12-372): 2.64e-131: 396: 29.75		H2B2F_HUMAN (5-127): 1.83e-54: 168: 85.37
+	Hs
		1026868 MK07_HUMAN (12-372): 2.64e-131: 396: 29.75		H2B1H_HUMAN (5-127): 5.52e-54: 166: 85.37
+	Hs
		1026874 MK07_HUMAN (12-372): 2.64e-131: 396: 29.75		H2B1N_HUMAN (1-127): 1.22e-53: 166: 85.83
+	Hs
		241518 MK07_HUMAN (12-372): 2.64e-131: 396: 29.75		H2B1K_HUMAN (1-127): 8.56e-54: 166: 84.25
+	Hs
		883013 MK07_HUMAN (12-372): 2.64e-131: 396: 29.75		H2BFS_HUMAN (1-127): 8.37e-54: 166: 82.68
+	Hs
		886098 MK07_HUMAN (12-372): 2.64e-131: 396: 29.75		H2B1D_HUMAN (1-127): 1.37e-53: 166: 85.04
+	Hs
		918333 MK07_HUMAN (12-372): 2.64e-131: 396: 29.75		H2B1C_HUMAN (1-127): 8.19e-54: 166: 85.04
+	Hs
		1026876 MK07_HUMAN (12-372): 2.64e-131: 396: 29.75		H2B1L_HUMAN (1-127): 1.35e-52: 163: 85.83
+	Hs
		625471 CDK2_HUMAN (16-321): 4.46e-136: 391: 38.76		H2B2E_HUMAN (1-127): 4.39e-54: 167: 85.83
+	Hs
		625165 CDK2_HUMAN (16-321): 4.46e-136: 391: 38.76		H2B1B_HUMAN (1-127): 6.87e-54: 166: 85.83
+	Rn
		926453 MK01_RAT (5-359): 1.31e-131: 382: 30.99		H2B1_RAT (1-127): 1e-50: 158: 81.89
+	Hs
		414779 CDK1_HUMAN (16-315): 5.07e-124: 361: 40.40		H2B1B_HUMAN (1-127): 6.87e-54: 166: 85.83
+	Hs
		241504 CDK5_HUMAN (16-321): 3.24e-118: 346: 39.74		H2B1K_HUMAN (1-127): 8.56e-54: 166: 84.25
+	Hs
		918294 CDK5_HUMAN (16-321): 3.24e-118: 346: 39.74		H2B1C_HUMAN (1-127): 8.19e-54: 166: 85.04
+	Sc
		355998 CTK1_YEAST (17-331): 3.26e-72: 235: 39.25		H2B2_YEAST (4-126): 4.46e-41: 134: 69.36
+	Sc
		355787 BUR1_YEAST (19-323): 6.47e-69: 230: 41.30		H2B2_YEAST (4-126): 4.46e-41: 134: 69.36