HitPredict

Interactor 1: WASP (P42768)
Actin nucleation-promoting factor WAS (Wiskott-Aldrich syndrome protein) (WASp)
Gene: WAS

Interactor 2: ABI3 (Q9P2A4)
ABI gene family member 3 (New molecule including SH3) (Nesh)
Gene: ABI3

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.50	0.584

Property	Details
Experiments	25416956, 21516116
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 502 Hs			1 366
+	Rn
		148378 WASL_RAT (12-310): 4.48e-119: 360: 47.35		SRC8_RAT (40-363): 8.53e-44: 160: 13.89
+	Hs
		133698 WASL_HUMAN (15-311): 1.14e-115: 352: 47.67		PACN2_HUMAN (17-363): 4.81e-45: 162: 14.29
+	Mm
		1221190 WASL_MOUSE (12-310): 6.52e-118: 357: 47.68		SRC8_MOUSE (40-363): 6.97e-42: 155: 13.44
+	Hs
		133661 WASL_HUMAN (15-311): 1.14e-115: 352: 47.67		SRC8_HUMAN (40-363): 4.99e-43: 158: 16.12
+	Hs
		133687 WASL_HUMAN (15-311): 1.14e-115: 352: 47.67		PACN1_HUMAN (11-363): 1.32e-37: 142: 12.67
+	Hs
		842672 WASP_HUMAN (1-487): 7.13e-99: 308: 100.00		PACN2_HUMAN (17-363): 4.81e-45: 162: 14.29
+	Hs
		842649 WASP_HUMAN (1-487): 7.13e-99: 308: 100.00		SRC8_HUMAN (40-363): 4.99e-43: 158: 16.12
+	Hs
		133692 WASL_HUMAN (15-311): 1.14e-115: 352: 47.67		ABI2_HUMAN (109-363): 1.97e-25: 108: 23.18
+	Hs
		842664 WASP_HUMAN (1-487): 7.13e-99: 308: 100.00		PACN1_HUMAN (11-363): 1.32e-37: 142: 12.67
+	Hs
		571659 WASP_HUMAN (1-487): 7.13e-99: 308: 100.00		HCLS1_HUMAN (20-363): 4.03e-37: 141: 13.98
+	Rn
		98626 F1LSG0_RAT (12-310): 6.91e-120: 362: 47.68		ITSN1_RAT (294-363): 6.82e-13: 72.1: 35.14
+	Hs
		133669 WASL_HUMAN (15-311): 1.14e-115: 352: 47.67		SH3R1_HUMAN (254-363): 8.68e-14: 74.7: 20.91
+	Hs
		133656 WASL_HUMAN (15-311): 1.14e-115: 352: 47.67		GRB2_HUMAN (312-363): 4.05e-14: 72.7: 28.30
+	Hs
		133694 WASL_HUMAN (15-311): 1.14e-115: 352: 47.67		ITSN2_HUMAN (306-365): 5.4e-13: 72.7: 37.50
+	Hs
		133663 WASL_HUMAN (15-311): 1.14e-115: 352: 47.67		ITSN1_HUMAN (205-363): 5.28e-10: 63.2: 15.85
+	Dm
		1468344 Q9VAT0_DROME (13-398): 5.52e-75: 247: 34.33		Q9VDI1_DROME (2-363): 4.84e-35: 135: 12.59
+	Hs
		842635 WASP_HUMAN (1-487): 7.13e-99: 308: 100.00		GRB2_HUMAN (312-363): 4.05e-14: 72.7: 28.30
+	Hs
		842666 WASP_HUMAN (1-487): 7.13e-99: 308: 100.00		ITSN2_HUMAN (306-365): 5.4e-13: 72.7: 37.50
+	Hs
		842654 WASP_HUMAN (1-487): 7.13e-99: 308: 100.00		ITSN1_HUMAN (205-363): 5.28e-10: 63.2: 15.85
+	Dm
		118289 Q9VAT0_DROME (13-398): 5.52e-75: 247: 34.33		M9ND00_DROME (109-364): 5.15e-22: 99.7: 14.72