HitPredict

Interactor 1: WASL (O00401)
Actin nucleation-promoting factor WASL (Neural Wiskott-Aldrich syndrome protein) (N-WASP)
Gene: WASL

Interactor 2: SRC8 (Q14247)
Src substrate cortactin (Amplaxin) (Oncogene EMS1)
Gene: CTTN

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

Property	Details
Experiments	11830518, 12672817
Identification Methods	far western blotting, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0030027 - lamellipodium GO:0030036 - actin cytoskeleton organization GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 505 Hs			1 550
+	Hs
		215920 SYNJ1_HUMAN (4-500): 4.16e-62: 222: 14.85		MYO1E_HUMAN (165-549): 9.91e-45: 172: 15.01
+	Hs
		215960 SYNJ1_HUMAN (4-500): 4.16e-62: 222: 14.85		PACN2_HUMAN (176-550): 1.85e-40: 154: 15.37
+	Rn
		204412 SYNJ1_RAT (4-505): 7.77e-69: 241: 13.31		SH3G3_RAT (365-549): 5.62e-32: 128: 19.36
+	Rn
		205732 SYNJ1_RAT (4-505): 7.77e-69: 241: 13.31		SH3G1_RAT (365-549): 1.59e-31: 127: 17.01
+	Rn
		204410 SYNJ1_RAT (4-505): 7.77e-69: 241: 13.31		SH3G2_RAT (365-549): 8.9e-31: 124: 17.28
+	Hs
		215948 SYNJ1_HUMAN (4-500): 4.16e-62: 222: 14.85		PACN1_HUMAN (241-549): 2.38e-31: 128: 16.86
+	Hs
		215946 SYNJ1_HUMAN (4-500): 4.16e-62: 222: 14.85		SH3G2_HUMAN (365-549): 1.88e-31: 126: 17.28
+	Hs
		215945 SYNJ1_HUMAN (4-500): 4.16e-62: 222: 14.85		SH3G1_HUMAN (365-549): 6.54e-31: 125: 17.01
+	Mm
		92772 D3Z656_MOUSE (4-505): 5.94e-61: 218: 13.01		SH3G2_MOUSE (365-549): 4.62e-31: 125: 17.80
+	Mm
		92773 D3Z656_MOUSE (4-505): 5.94e-61: 218: 13.01		SH3G3_MOUSE (365-549): 4.55e-31: 125: 19.89
+	Dm
		1468348 Q9VAT0_DROME (1-504): 8.82e-57: 199: 31.37		DBNL_DROME (208-549): 6.59e-34: 136: 20.53
+	Rn
		204812 SYNJ1_RAT (4-505): 7.77e-69: 241: 13.31		SRBS2_RAT (452-549): 1.6e-11: 69.2: 22.00
+	Hs
		176277 SYNJ2_HUMAN (3-471): 6.59e-60: 215: 14.85		ITSN2_HUMAN (398-548): 1.25e-18: 92.3: 17.88
+	Hs
		215925 SYNJ1_HUMAN (4-500): 4.16e-62: 222: 14.85		ITSN1_HUMAN (165-548): 6.15e-15: 80.5: 11.99
+	Hs
		215885 SYNJ1_HUMAN (4-500): 4.16e-62: 222: 14.85		VINEX_HUMAN (254-546): 4.07e-13: 73.9: 13.51
+	Hs
		176266 SYNJ2_HUMAN (3-471): 6.59e-60: 215: 14.85		ITSN1_HUMAN (165-548): 6.15e-15: 80.5: 11.99
+	Hs
		215886 SYNJ1_HUMAN (4-500): 4.16e-62: 222: 14.85		SRBS2_HUMAN (447-549): 1.7e-11: 69.2: 21.91
+	Dm
		118289 Q9VAT0_DROME (1-504): 8.82e-57: 199: 31.37		M9ND00_DROME (219-547): 1.48e-10: 66.4: 16.67
+	Hs
		323898 SC31A_HUMAN (10-495): 1.63e-51: 191: 10.39		STAM1_HUMAN (416-546): 2.83e-13: 74.4: 21.83
+	Dm
		1468346 Q9VAT0_DROME (1-504): 8.82e-57: 199: 31.37		Q9VIF7_DROME (219-547): 4.18e-10: 64.9: 16.67