HitPredict

Interactor 1: TCPD (P50991)
T-complex protein 1 subunit delta (TCP-1-delta) (CCT-delta) (Chaperonin containing T-complex polypeptide 1 subunit 4) (Stimulator of TAR RNA-binding)
Gene: CCT4

Interactor 2: ERCC8 (Q13216)
DNA excision repair protein ERCC-8 (Cockayne syndrome WD repeat protein CSA)
Gene: ERCC8

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29531219
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 539 Hs			1 396
+	Hs
		843357 TCPD_HUMAN (1-539): 0: 602: 100.00		TBL1Y_HUMAN (2-321): 1.67e-67: 224: 18.24
+	Hs
		826641 TCPG_HUMAN (12-537): 0: 553: 33.40		ERCC8_HUMAN (1-396): 7.48e-87: 270: 100.00
+	Hs
		843139 TCPD_HUMAN (1-539): 0: 602: 100.00		WDR5_HUMAN (218-396): 2.25e-46: 163: 20.44
+	Hs
		843273 TCPD_HUMAN (1-539): 0: 602: 100.00		WDR5B_HUMAN (220-396): 1.61e-42: 153: 18.99
+	Hs
		843299 TCPD_HUMAN (1-539): 0: 602: 100.00		POC1B_HUMAN (228-395): 1.45e-33: 132: 15.29
+	Hs
		826601 TCPG_HUMAN (12-537): 0: 553: 33.40		WDR5_HUMAN (218-396): 2.25e-46: 163: 20.44
+	Hs
		843289 TCPD_HUMAN (1-539): 0: 602: 100.00		POC1A_HUMAN (4-130): 3.18e-24: 105: 13.38
+	Hs
		826748 TCPG_HUMAN (12-537): 0: 553: 33.40		WDR5B_HUMAN (220-396): 1.61e-42: 153: 18.99
+	Hs
		792942 TCPG_HUMAN (12-537): 0: 553: 33.40		LIS1_HUMAN (218-395): 1.1e-38: 145: 14.44
+	Hs
		826784 TCPG_HUMAN (12-537): 0: 553: 33.40		POC1B_HUMAN (228-395): 1.45e-33: 132: 15.29
+	Hs
		843411 TCPD_HUMAN (1-539): 0: 602: 100.00		NLE1_HUMAN (3-71): 4.91e-16: 81.3: 18.57
+	Hs
		843214 TCPD_HUMAN (1-539): 0: 602: 100.00		RBBP7_HUMAN (129-368): 4.26e-15: 78.3: 19.22
+	Hs
		843174 TCPD_HUMAN (1-539): 0: 602: 100.00		CDC20_HUMAN (69-352): 8.11e-11: 65.5: 23.81
+	Hs
		196979 TCPD_HUMAN (1-539): 0: 602: 100.00		PRP4_HUMAN (89-272): 1.17e-10: 65.1: 26.27
+	Hs
		826772 TCPG_HUMAN (12-537): 0: 553: 33.40		POC1A_HUMAN (4-130): 3.18e-24: 105: 13.38
+	Sc
		760979 TCPD_YEAST (22-539): 0: 570: 59.20		RAD28_YEAST (98-272): 1.54e-12: 70.9: 26.80
+	Ce
		954097 Q9TZS5_CAEEL (12-538): 0: 557: 31.52		LIN53_CAEEL (98-276): 1.11e-09: 61.6: 25.82
+	Hs
		826632 TCPG_HUMAN (12-537): 0: 553: 33.40		CDC20_HUMAN (69-352): 8.11e-11: 65.5: 23.81
+	Hs
		196973 TCPG_HUMAN (12-537): 0: 553: 33.40		PRP4_HUMAN (89-272): 1.17e-10: 65.1: 26.27
+	Ce
		812719 TCPD_CAEEL (20-538): 0: 555: 63.65		LIN53_CAEEL (98-276): 1.11e-09: 61.6: 25.82