HitPredict

Interactor 1: TNR4 (P43489)
Tumor necrosis factor receptor superfamily member 4 (ACT35 antigen) (OX40L receptor) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD antigen CD134)
Gene: TNFRSF4

Interactor 2: TRAF1 (Q13077)
TNF receptor-associated factor 1 (Epstein-Barr virus-induced protein 6)
Gene: TRAF1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.50	0.470

Property	Details
Experiments	15941918
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 277 Hs			1 416
+	Mm
		811867 TNR4_MOUSE (23-277): 8.86e-64: 203: 62.26		TRAF1_MOUSE (1-416): 3.7e-160: 459: 84.38
+	Hs
		630264 TNR1B_HUMAN (21-248): 5.87e-43: 154: 22.10		TRAF1_HUMAN (1-416): 4.48e-172: 489: 100.00
+	Hs
		1094005 TNR11_HUMAN (28-181): 3.63e-36: 137: 26.40		TRAF1_HUMAN (1-416): 4.48e-172: 489: 100.00
+	Hs
		849432 TNR4_HUMAN (1-277): 7.01e-70: 218: 100.00		TRAF2_HUMAN (3-415): 5.31e-124: 370: 38.01
+	Mm
		811896 TNR4_MOUSE (23-277): 8.86e-64: 203: 62.26		TRAF2_MOUSE (3-415): 4.36e-127: 378: 37.77
+	Mm
		204645 TNR11_MOUSE (6-181): 1.18e-41: 153: 27.59		TRAF2_MOUSE (3-415): 4.36e-127: 378: 37.77
+	Hs
		630262 TNR1B_HUMAN (21-248): 5.87e-43: 154: 22.10		TRAF2_HUMAN (3-415): 5.31e-124: 370: 38.01
+	Hs
		1091000 TNR11_HUMAN (28-181): 3.63e-36: 137: 26.40		TRAF2_HUMAN (3-415): 5.31e-124: 370: 38.01
+	Hs
		630385 TNR1B_HUMAN (21-248): 5.87e-43: 154: 22.10		TRAF6_HUMAN (15-414): 3.23e-103: 317: 22.98
+	Mm
		204647 TNR11_MOUSE (6-181): 1.18e-41: 153: 27.59		TRAF6_MOUSE (15-414): 5.28e-101: 312: 22.51
+	Hs
		1491435 TNR11_HUMAN (28-181): 3.63e-36: 137: 26.40		TRAF6_HUMAN (15-414): 3.23e-103: 317: 22.98
+	Hs
		136668 TNR4_HUMAN (1-277): 7.01e-70: 218: 100.00		TRAF5_HUMAN (14-261): 1.06e-16: 83.8: 13.91
+	Hs
		849434 TNR4_HUMAN (1-277): 7.01e-70: 218: 100.00		TRAF3_HUMAN (3-262): 8.09e-11: 65.7: 15.77
+	Hs
		849435 TNR4_HUMAN (1-277): 7.01e-70: 218: 100.00		TRAF4_HUMAN (27-136): 2.85e-09: 60.7: 17.86
+	Mm
		866565 TNR4_MOUSE (23-277): 8.86e-64: 203: 62.26		TRAF3_MOUSE (1-262): 1.98e-12: 70.7: 16.37
+	Mm
		204646 TNR11_MOUSE (6-181): 1.18e-41: 153: 27.59		TRAF5_MOUSE (14-296): 5.67e-13: 72.7: 13.45
+	Mm
		204649 TNR11_MOUSE (6-181): 1.18e-41: 153: 27.59		TRAF3_MOUSE (1-262): 1.98e-12: 70.7: 16.37
+	Hs
		136737 TNR11_HUMAN (28-181): 3.63e-36: 137: 26.40		TRAF5_HUMAN (14-261): 1.06e-16: 83.8: 13.91
+	Hs
		630265 TNR1B_HUMAN (21-248): 5.87e-43: 154: 22.10		TRAF3_HUMAN (3-262): 8.09e-11: 65.7: 15.77
+	Hs
		1095019 TNR11_HUMAN (28-181): 3.63e-36: 137: 26.40		TRAF3_HUMAN (3-262): 8.09e-11: 65.7: 15.77