HitPredict

Interactor 1: UB2D1 (P51668)
Ubiquitin-conjugating enzyme E2 D1 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme D1) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme D1) (Stimulator of Fe transport) (SFT) (UBC4/5 homolog) (UbcH5) (Ubiquitin carrier protein D1) (Ubiquitin-conjugating enzyme E2(17)KB 1) (Ubiquitin-conjugating enzyme E2-17 kDa 1) (Ubiquitin-protein ligase D1)
Gene: UBE2D1

Interactor 2: TRI55 (Q9BYV6)
Tripartite motif-containing protein 55 (EC 2.3.2.27) (Muscle-specific RING finger protein 2) (MuRF-2) (MuRF2) (RING finger protein 29)
Gene: TRIM55

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	1.00	0.698

Property	Details
Experiments	19549727
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	UQ_con~zf-RING_UBOX
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0061630 - ubiquitin protein ligase activity GO:0070936 - protein K48-linked ubiquitination
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 147 Hs			1 548
+	Hs
		262201 UB2D4_HUMAN (1-147): 1.29e-82: 241: 91.84		TRIM3_HUMAN (7-525): 5.4e-80: 267: 16.64
+	Hs
		262161 UB2D1_HUMAN (1-147): 3.24e-82: 239: 100.00		TRIM3_HUMAN (7-525): 5.4e-80: 267: 16.64
+	Hs
		1336390 UB2D4_HUMAN (1-147): 1.29e-82: 241: 91.84		TRI39_HUMAN (17-414): 4.23e-77: 254: 15.74
+	Hs
		1317493 UB2D4_HUMAN (1-147): 1.29e-82: 241: 91.84		TRI54_HUMAN (1-353): 3.29e-78: 252: 62.54
+	Hs
		1318738 UB2D4_HUMAN (1-147): 1.29e-82: 241: 91.84		TRIM2_HUMAN (6-525): 1.61e-74: 252: 16.48
+	Hs
		584907 UB2D1_HUMAN (1-147): 3.24e-82: 239: 100.00		RO52_HUMAN (12-405): 3.8e-74: 245: 15.87
+	Hs
		1285831 UB2D4_HUMAN (1-147): 1.29e-82: 241: 91.84		TRI43_HUMAN (13-395): 3.07e-73: 242: 13.06
+	Hs
		1318719 UB2D4_HUMAN (1-147): 1.29e-82: 241: 91.84		TRIM5_HUMAN (13-396): 3.08e-68: 230: 14.32
+	Hs
		1151762 UB2D4_HUMAN (1-147): 1.29e-82: 241: 91.84		Q6GX22_HUMAN (17-367): 1.43e-63: 222: 21.28
+	Hs
		1318358 UB2D4_HUMAN (1-147): 1.29e-82: 241: 91.84		TRIM8_HUMAN (18-465): 8.09e-65: 222: 18.25
+	Hs
		1356055 UB2D4_HUMAN (1-147): 1.29e-82: 241: 91.84		TRIM1_HUMAN (17-367): 3.2e-63: 222: 21.28
+	Hs
		537142 UB2D4_HUMAN (1-147): 1.29e-82: 241: 91.84		TRI27_HUMAN (12-434): 9.25e-65: 221: 14.51
+	Ce
		715104 UBC2_CAEEL (1-147): 7.45e-82: 239: 89.12		NHL1_CAEEL (1-517): 2.07e-62: 223: 17.32
+	Hs
		849314 UB2D1_HUMAN (1-147): 3.24e-82: 239: 100.00		TRI26_HUMAN (12-339): 5.62e-65: 222: 16.23
+	Hs
		536760 UB2D1_HUMAN (1-147): 3.24e-82: 239: 100.00		TRI27_HUMAN (12-434): 9.25e-65: 221: 14.51
+	Hs
		1313765 UB2D4_HUMAN (1-147): 1.29e-82: 241: 91.84		TRI62_HUMAN (19-289): 8.04e-64: 217: 20.80
+	Hs
		1318532 UB2D4_HUMAN (1-147): 1.29e-82: 241: 91.84		TRI31_HUMAN (12-426): 1.42e-62: 213: 17.35
+	Hs
		1377469 UB2D4_HUMAN (1-147): 1.29e-82: 241: 91.84		TRI17_HUMAN (18-368): 7.08e-62: 212: 16.71
+	Hs
		175730 UB2D4_HUMAN (1-147): 1.29e-82: 241: 91.84		TRI18_HUMAN (46-330): 5.85e-60: 211: 23.43
+	Hs
		175653 UB2D1_HUMAN (1-147): 3.24e-82: 239: 100.00		TRI18_HUMAN (46-330): 5.85e-60: 211: 23.43