HitPredict

Interactor 1: SKP1 (P52286)
Suppressor of kinetochore protein 1 (Centromere DNA-binding protein complex CBF3 subunit D) (E3 ubiquitin ligase complex SCF subunit SKP1)
Gene: SKP1

Interactor 2: CDC53 (Q12018)
Cell division control protein 53 (Cullin-A) (E3 ubiquitin ligase complex SCF subunit CDC53)
Gene: CDC53

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 1.00 0.993

The method score is based on:

Property Details
Experiments 9346238, 9499404, 13678584, 11283612, 10688190, 12676951, 10213692, 10213691, 11805837, 16421250, 11287615, 9346239, 15660125, 16432255, 10445024, 21172660, 20581845, 19942853, 23000173, 14747994 and 8 others

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Identification Methods coimmunoprecipitation, two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation, biochemical, pull down, miniaturized immunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Cullin~Skp1_POZ
Common GO terms GO:0000082 - G1/S transition of mitotic cell cycle
GO:0000086 - G2/M transition of mitotic cell cycle
GO:0000409 - regulation of transcription by galactose
GO:0000781 - chromosome, telomeric region
GO:0003688 - DNA replication origin binding
and 15 others

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Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 194
Sc

1 815
+ Mm
+ Hs
+ Dm
+ Hs
+ Hs
+ Hs
+ Dm
+ Ce
+ Sp
+ At
+ Hs
+ At
+ At
+ At
+ Ce
+ Dm
+ At
+ At
+ Hs
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024