Protein: PRUN2
Protein prune homolog 2 (BNIP2 motif-containing molecule at the C-terminal region 1)

Gene: PRUN2, PRUNE2
Organism: Homo sapiens
Interactions: 38
UniProt ID: Q8WUY3

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006915 - apoptotic process
GO:0016462 - pyrophosphatase activity
GO:0046872 - metal ion binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

440649

FYN
Tyrosine-protein kinase Fyn

2

5

High-throughput

0.606

High

255460

SNX2
Sorting nexin-2

1

2

High-throughput

0.536

High

463177

YES
Tyrosine-protein kinase Yes

1

5

High-throughput

0.536

High

557402

SRC
Proto-oncogene tyrosine-protein kinase Src

1

5

High-throughput

0.536

High

1111948

SNX1
Sorting nexin-1

1

2

High-throughput

0.536

High

1357358

SNX6
Sorting nexin-6

1

2

High-throughput

0.536

High

1033090

EWS
RNA-binding protein EWS

1

0

High-throughput

0.518

High

384706

CRYAB
Alpha-crystallin B chain

1

1

High-throughput

0.515

High

415748

HSPB1
Heat shock protein beta-1

1

1

High-throughput

0.515

High

593773

PECA1
Platelet endothelial cell adhesion molecule

1

2

High-throughput

0.515

High

1357352

UBCP1
Ubiquitin-like domain-containing CTD phosphatase 1

1

0

High-throughput

0.513

High

1357354

RCN3
Reticulocalbin-3

1

1

High-throughput

0.494

High

167338

KLF11
Krueppel-like factor 11

1

0

High-throughput

0.493

High

409010

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

0

High-throughput

0.493

High

461756

HS90A
Heat shock protein HSP 90-alpha

1

0

High-throughput

0.493

High

474855

VIME
Vimentin

1

0

High-throughput

0.493

High

532807

CH60
60 kDa heat shock protein, mitochondrial

1

0

High-throughput

0.493

High

660284

BDNF
Neurotrophic factor BDNF precursor form

1

0

High-throughput

0.493

High

728349

AKT1
RAC-alpha serine/threonine-protein kinase

1

0

High-throughput

0.493

High

843804

HD
Huntingtin

1

0

High-throughput

0.493

High

856834

BAG6
Large proline-rich protein BAG6

1

0

High-throughput

0.493

High

957636

UBE2K
Ubiquitin-conjugating enzyme E2 K

1

0

High-throughput

0.493

High

1357353

APBB2
Amyloid beta precursor protein binding family B member 2

1

0

High-throughput

0.493

High

1210729

ZMYM1
Zinc finger MYM-type protein 1

1

1

High-throughput

0.489

High

1357355

MLP3B
Microtubule-associated protein 1 light chain 3 beta

1

0

High-throughput

0.480

High

463674

LYN
Tyrosine-protein kinase Lyn

1

5

Small-scale

0.479

High

522117

BCL2
Apoptosis regulator Bcl-2

1

3

Small-scale

0.479

High

1357357

WSB2
WD repeat and SOCS box-containing protein 2

1

1

High-throughput

0.479

High

133776

PDE2A
cGMP-dependent 3',5'-cyclic phosphodiesterase

1

0

High-throughput

0.458

High

272343

OBSL1
Obscurin-like protein 1

1

0

High-throughput

0.458

High

1276245

ATG9A
Autophagy-related protein 9A

1

3

High-throughput

0.437

High

1357356

PLCE
1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon

1

2

High-throughput

0.437

High

934909

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.426

High

1103288

CTBP1
C-terminal-binding protein 1

1

0

High-throughput

0.426

High

380325

DRA
HLA class II histocompatibility antigen, DR alpha chain

1

0

High-throughput

0.269

Low

940028

NDUV3
NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial

1

0

High-throughput

0.269

Low

301594

WFS1
Wolframin

1

0

High-throughput

0.268

Low

389861

TTHY
Transthyretin

1

0

High-throughput

0.268

Low


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Last updated: 11Aug2025