HitPredict

Interactor 1: CRKL (P46109)
Crk-like protein
Gene: CRKL

Interactor 2: Q6NSK7 (Q6NSK7)
RIN3 protein
Gene: RIN3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.50	0.417

Property	Details
Experiments	unassigned1973
Identification Methods	two hybrid fragment pooling approach
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 303 Hs			1 908
+	Hs
		855649 CRK_HUMAN (3-302): 1.42e-51: 173: 54.89		Q6NSK7_HUMAN (1-908): 0: 666: 100.00
+	Hs
		855906 CRKL_HUMAN (1-303): 1.48e-70: 222: 100.00		RIN3_HUMAN (1-908): 0: 586: 89.04
+	Hs
		3238 A0A0S2Z3Q4_HUMAN (3-302): 1.42e-51: 173: 54.89		RIN3_HUMAN (1-908): 0: 586: 89.04
+	Hs
		855694 CRK_HUMAN (3-302): 1.42e-51: 173: 54.89		RIN3_HUMAN (1-908): 0: 586: 89.04
+	Hs
		1237986 ITSN2_HUMAN (73-297): 1.66e-16: 82.1: 16.89		Q6NSK7_HUMAN (1-908): 0: 666: 100.00
+	Hs
		594023 NCK1_HUMAN (85-196): 2.66e-16: 80.2: 22.81		Q6NSK7_HUMAN (1-908): 0: 666: 100.00
+	Hs
		292853 GRAP2_HUMAN (3-291): 5.54e-38: 138: 14.53		RIN3_HUMAN (1-908): 0: 586: 89.04
+	Hs
		1195624 Q4LE43_HUMAN (5-253): 3.15e-28: 116: 16.60		RIN3_HUMAN (1-908): 0: 586: 89.04
+	Hs
		619080 PLCG1_HUMAN (5-253): 8.29e-28: 115: 16.60		RIN3_HUMAN (1-908): 0: 586: 89.04
+	Hs
		72726 B0LPF3_HUMAN (126-295): 3.56e-23: 96.8: 15.89		RIN3_HUMAN (1-908): 0: 586: 89.04
+	Hs
		987787 GRB2_HUMAN (126-295): 3.56e-23: 96.8: 15.89		RIN3_HUMAN (1-908): 0: 586: 89.04
+	Hs
		1347881 ITSN2_HUMAN (73-297): 1.66e-16: 82.1: 16.89		RIN3_HUMAN (1-908): 0: 586: 89.04
+	Hs
		594053 NCK1_HUMAN (85-196): 2.66e-16: 80.2: 22.81		RIN3_HUMAN (1-908): 0: 586: 89.04
+	Hs
		73623 B2R6S4_HUMAN (85-196): 2.49e-16: 80.2: 22.81		RIN3_HUMAN (1-908): 0: 586: 89.04
+	Hs
		913651 VAV2_HUMAN (14-180): 4.48e-40: 150: 19.80		GAPD1_HUMAN (155-765): 5.28e-72: 262: 15.84
+	Hs
		855883 CRKL_HUMAN (1-303): 1.48e-70: 222: 100.00		TENS2_HUMAN (3-217): 4.91e-32: 137: 19.33
+	Hs
		987699 GRB2_HUMAN (126-295): 3.56e-23: 96.8: 15.89		TENS2_HUMAN (3-217): 4.91e-32: 137: 19.33
+	Ce
		145093 VAV_CAEEL (14-185): 2.46e-26: 111: 21.91		UNC89_CAEEL (6-370): 2.05e-09: 64: 11.29
+	Hs
		215914 GRB2_HUMAN (126-295): 3.56e-23: 96.8: 15.89		SYNJ1_HUMAN (103-493): 1.38e-09: 64.4: 13.65
+	Hs
		215903 NCK1_HUMAN (85-196): 2.66e-16: 80.2: 22.81		SYNJ1_HUMAN (103-493): 1.38e-09: 64.4: 13.65