Interactor 1: NOTC1 (P46531)
Neurogenic locus notch homolog protein 1 (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)]
Gene: NOTCH1
Interactor 2: EGFL7 (Q9UHF1)
Epidermal growth factor-like protein 7 (EGF-like protein 7) (Multiple epidermal growth factor-like domains protein 7) (Multiple EGF-like domains protein 7) (NOTCH4-like protein) (Vascular endothelial statin) (VE-statin) (Zneu1)
Gene: EGFL7
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.46 | 1.00 | 0.680 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 19503073 |
| Identification Methods | two hybrid, pull down |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | EGF~FXa_inhibition, EGF_CA~FXa_inhibition |
| Common GO terms | GO:0005509 - calcium ion binding GO:0005576 - extracellular region GO:0009986 - cell surface |
| Homologous interactions | 19 |
Homologous interactions
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025