HitPredict

Interactor 1: NOTCH (P07207)
Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein]
Gene: N

Interactor 2: SERR (P18168)
Protein serrate (Protein beaded)
Gene: Ser

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 1.00 0.925

The method score is based on:

Property Details
Experiments 23970418, 23197537, 17923477, 31722217, 15804562, unassigned4
Identification Methods affinity chromatography technology, experimental interaction detection
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains EGF~EGF, DL-JAG_EGF-like~EGF, EGF~hEGF, DSL~EGF_CA, EGF~EGF_CA, EGF_CA~hEGF, EGF_CA~MNNL, MNNL~hEGF
Common GO terms GO:0005509 - calcium ion binding
GO:0005886 - plasma membrane
GO:0007219 - Notch signaling pathway
GO:0007423 - sensory organ development
GO:0007476 - imaginal disc-derived wing morphogenesis
and 13 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

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Service provided by Combinatics, Japan

Last updated: 11Aug2025