Interactor 1: M3K1 (P53349)
Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1)
Gene: Map3k1

Interactor 2: JIP3 (Q9ESN9)
C-Jun-amino-terminal kinase-interacting protein 3 (JIP-3) (JNK-interacting protein 3) (JNK MAP kinase scaffold protein 3) (JNK/SAPK-associated protein 1) (JSAP1) (Mitogen-activated protein kinase 8-interacting protein 3) (Sunday driver 2)
Gene: Mapk8ip3

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 0.60 0.500

The method score is based on:

Property Details
Experiments 10523642
Identification Methods pull down
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0007254 - JNK cascade
GO:0008432 - JUN kinase binding
GO:0031434 - mitogen-activated protein kinase kinase binding
GO:0043507 - positive regulation of JUN kinase activity
and 1 others

more...

Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 1493
Mm

1 1337
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Mm
+ Hs
+ Hs

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Last updated: 15 Jul 2024