HitPredict

Interactor 1: FBW1A (Q9Y297)
F-box/WD repeat-containing protein 1A (E3RSIkappaB) (Epididymis tissue protein Li 2a) (F-box and WD repeats protein beta-TrCP) (pIkappaBalpha-E3 receptor subunit)
Gene: BTRC

Interactor 2: NCOR2 (Q9Y618)
Nuclear receptor corepressor 2 (N-CoR2) (CTG repeat protein 26) (SMAP270) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (T3 receptor-associating factor) (TRAC) (Thyroid-, retinoic-acid-receptor-associated corepressor)
Gene: NCOR2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	23861398
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 605 Hs			1 2514
+	Hs
		1346974 NLE1_HUMAN (33-408): 1.35e-41: 159: 13.21		NCOR2_HUMAN (1-2514): 0: 908: 100.00
+	Hs
		245652 TBL1X_HUMAN (501-605): 3.8e-15: 80.4: 19.13		NCOR2_HUMAN (1-2514): 0: 908: 100.00
+	Hs
		1329253 FBW1B_HUMAN (96-605): 1.89e-143: 428: 85.69		TARA_HUMAN (40-1577): 3.75e-52: 206: 9.68
+	Hs
		1146262 FBW1A_HUMAN (1-605): 0: 551: 100.00		MAP1S_HUMAN (677-1123): 3.28e-13: 77.7: 15.77
+	Xl
		1093463 TB1RA_XENLA (501-605): 3.97e-15: 80.4: 16.67		Q1W3Z6_XENLA (4-2514): 7.45e-150: 523: 51.60
+	Hs
		245548 TBL1X_HUMAN (501-605): 3.8e-15: 80.4: 19.13		NCOR1_HUMAN (1-2514): 9.88e-128: 453: 34.38
+	Hs
		261584 TBL1R_HUMAN (501-605): 3.85e-15: 80.4: 16.67		NCOR1_HUMAN (1-2514): 9.88e-128: 453: 34.38
+	Xl
		1186358 TB1RA_XENLA (501-605): 3.97e-15: 80.4: 16.67		NCOR1_XENLA (1-2514): 7.28e-122: 434: 32.87
+	Hs
		1146258 FBW1B_HUMAN (96-605): 1.89e-143: 428: 85.69		MAP1S_HUMAN (677-1123): 3.28e-13: 77.7: 15.77
+	Hs
		1281467 FBXW7_HUMAN (76-527): 7.38e-83: 276: 23.71		RCOR1_HUMAN (388-705): 2.51e-45: 174: 22.05
+	Hs
		793042 LIS1_HUMAN (174-494): 8.99e-74: 243: 21.37		SRRM2_HUMAN (11-1905): 4.06e-30: 133: 8.95
+	Hs
		1281391 FBXW7_HUMAN (76-527): 7.38e-83: 276: 23.71		PRR36_HUMAN (2-1025): 1.03e-10: 69.6: 8.95
+	Hs
		1346970 NLE1_HUMAN (33-408): 1.35e-41: 159: 13.21		SRRM2_HUMAN (11-1905): 4.06e-30: 133: 8.95
+	Dm
		1370339 FBXW7_DROME (414-604): 1.53e-53: 199: 30.73		Q9VLS7_DROME (674-1534): 4.08e-09: 64.5: 13.10
+	Hs
		1302927 NLE1_HUMAN (33-408): 1.35e-41: 159: 13.21		MINT_HUMAN (80-1321): 6.8e-20: 100: 8.11
+	Hs
		245648 TBL1X_HUMAN (501-605): 3.8e-15: 80.4: 19.13		RCOR1_HUMAN (388-705): 2.51e-45: 174: 22.05
+	Hs
		903450 WDR5_HUMAN (458-605): 5.01e-38: 145: 25.33		CIC_HUMAN (7-2131): 8.47e-18: 93.5: 9.33
+	Mm
		1206786 TBL1X_MOUSE (501-605): 3.79e-15: 80.4: 19.13		Q8BK32_MOUSE (1-280): 1.47e-40: 155: 49.66
+	Mm
		1206586 TBL1R_MOUSE (501-605): 5.38e-15: 80: 16.67		Q8BK32_MOUSE (1-280): 1.47e-40: 155: 49.66
+	Hs
		903374 WDR5_HUMAN (458-605): 5.01e-38: 145: 25.33		KMT2C_HUMAN (679-1264): 4.24e-16: 88: 11.93