HitPredict

Interactor 1: IQGA1 (P46940)
Ras GTPase-activating-like protein IQGAP1 (p195)
Gene: IQGAP1

Interactor 2: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.989

The method score is based on:

Property Details
Experiments 26496610, 31980649, 8798539, 8670801, 9182573, 9535855, 31871319, 35271311, 27684187, 12110184, 28524877, 15655247, 17563371, 21876773, 12377780, 18809683, unassigned2173, 12745076, 8702968
Identification Methods affinity chromatography technology, pull down, cross-linking study, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, coimmunoprecipitation, imaging technique
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Ras~RasGAP
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0005925 - focal adhesion
GO:0007165 - signal transduction
and 6 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1657
Hs

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Last updated: 11Aug2025