HitPredict

Interactor 1: B9EKJ1 (B9EKJ1)
Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain)
Gene: Sptan1

Interactor 2: HOME1 (Q9Z2Y3)
Homer protein homolog 1 (Homer-1) (VASP/Ena-related gene up-regulated during seizure and LTP 1) (Vesl-1)
Gene: Homer1

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	28671696
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2477 Mm			1 366
+	Mm
		98043 SPTA1_MOUSE (2-2477): 3.69e-155: 539: 54.04		DESP_MOUSE (72-361): 3.82e-09: 60.4: 12.62
+	Mm
		597668 SPTN1_MOUSE (1-1982): 5.66e-64: 245: 19.55		HOME1_MOUSE (1-366): 1.15e-85: 265: 100.00
+	Mm
		1229323 Q68FG2_MOUSE (5-1617): 2.2e-61: 236: 19.91		HOME1_MOUSE (1-366): 1.15e-85: 265: 100.00
+	Hs
		157346 SPTN1_HUMAN (1-1982): 1.05e-63: 244: 19.50		CTRO_HUMAN (12-364): 1.37e-45: 169: 13.04
+	Hs
		156700 SPTN2_HUMAN (5-1617): 2.42e-63: 243: 19.15		CTRO_HUMAN (12-364): 1.37e-45: 169: 13.04
+	Mm
		1223959 SPTB2_MOUSE (1-1194): 8.15e-34: 146: 18.56		HOME1_MOUSE (1-366): 1.15e-85: 265: 100.00
+	Hs
		896627 CP250_HUMAN (5-2204): 1.06e-72: 273: 9.44		VASP_HUMAN (1-359): 1.5e-34: 132: 15.51
+	Hs
		157329 GOGA4_HUMAN (2-1595): 8.52e-52: 205: 9.35		CTRO_HUMAN (12-364): 1.37e-45: 169: 13.04
+	Hs
		386450 SPTA1_HUMAN (1-2259): 1.06e-62: 241: 20.30		VASP_HUMAN (1-359): 1.5e-34: 132: 15.51
+	Hs
		157094 CENPF_HUMAN (321-2452): 9.83e-50: 198: 8.73		CTRO_HUMAN (12-364): 1.37e-45: 169: 13.04
+	Hs
		1117429 SPTN1_HUMAN (1-1982): 1.05e-63: 244: 19.50		MY18A_HUMAN (109-361): 6.1e-28: 117: 14.63
+	Hs
		174788 SPTN2_HUMAN (5-1617): 2.42e-63: 243: 19.15		MY18A_HUMAN (109-361): 6.1e-28: 117: 14.63
+	Hs
		156889 SPTB1_HUMAN (1-1630): 2.44e-42: 174: 18.56		CTRO_HUMAN (12-364): 1.37e-45: 169: 13.04
+	Hs
		1117523 SPTN1_HUMAN (1-1982): 1.05e-63: 244: 19.50		EVL_HUMAN (1-167): 3.32e-22: 98.9: 20.69
+	Hs
		386496 SPTA1_HUMAN (1-2259): 1.06e-62: 241: 20.30		EVL_HUMAN (1-167): 3.32e-22: 98.9: 20.69
+	Hs
		386476 SPTA1_HUMAN (1-2259): 1.06e-62: 241: 20.30		ENAH_HUMAN (1-235): 2.52e-19: 91.2: 19.67
+	Hs
		157994 MACF1_HUMAN (274-2421): 1.82e-36: 155: 9.46		CTRO_HUMAN (12-364): 1.37e-45: 169: 13.04
+	Hs
		157401 PLEC_HUMAN (1-1253): 5.21e-34: 147: 10.34		CTRO_HUMAN (12-364): 1.37e-45: 169: 13.04
+	Hs
		1143214 PLEC_HUMAN (1-1253): 5.21e-34: 147: 10.34		MY18A_HUMAN (109-361): 6.1e-28: 117: 14.63
+	Mm
		98081 PLEC_MOUSE (1-1275): 5.23e-38: 160: 10.31		DESP_MOUSE (72-361): 3.82e-09: 60.4: 12.62