HitPredict

Interactor 1: SC6A8 (P48029)
Sodium- and chloride-dependent creatine transporter 1 (CT1) (Creatine transporter 1) (Solute carrier family 6 member 8)
Gene: SLC6A8

Interactor 2: TRAM1 (Q15629)
Translocating chain-associated membrane protein 1 (Protein TRAM1)
Gene: TRAM1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	38070861, unassigned3795
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 635 Hs			1 374
+	Hs
		870238 S6A12_HUMAN (20-598): 0: 694: 54.47		TRAM1_HUMAN (1-374): 7.57e-142: 409: 100.00
+	Hs
		870362 S6A11_HUMAN (47-598): 0: 681: 57.14		TRAM1_HUMAN (1-374): 7.57e-142: 409: 100.00
+	Hs
		727562 SC6A4_HUMAN (7-597): 0: 665: 41.75		TRAM1_HUMAN (1-374): 7.57e-142: 409: 100.00
+	Hs
		869649 SC6A8_HUMAN (1-621): 0: 756: 100.00		CERS2_HUMAN (107-334): 4.23e-73: 233: 16.52
+	Hs
		693392 SC6A8_HUMAN (1-621): 0: 756: 100.00		CERS1_HUMAN (90-345): 3.1e-57: 191: 16.54
+	Hs
		1251764 SC6A5_HUMAN (38-626): 0: 716: 41.60		CERS6_HUMAN (107-335): 2.96e-71: 229: 19.48
+	Hs
		870285 S6A12_HUMAN (20-598): 0: 694: 54.47		CERS2_HUMAN (107-334): 4.23e-73: 233: 16.52
+	Hs
		870264 S6A12_HUMAN (20-598): 0: 694: 54.47		CERS5_HUMAN (106-330): 4.36e-72: 231: 19.82
+	Hs
		870399 S6A11_HUMAN (47-598): 0: 681: 57.14		CERS2_HUMAN (107-334): 4.23e-73: 233: 16.52
+	Hs
		870382 S6A11_HUMAN (47-598): 0: 681: 57.14		CERS5_HUMAN (106-330): 4.36e-72: 231: 19.82
+	Hs
		693393 S6A12_HUMAN (20-598): 0: 694: 54.47		CERS1_HUMAN (90-345): 3.1e-57: 191: 16.54
+	Hs
		693394 S6A11_HUMAN (47-598): 0: 681: 57.14		CERS1_HUMAN (90-345): 3.1e-57: 191: 16.54
+	Hs
		1150609 S6A15_HUMAN (360-579): 1.15e-57: 209: 32.04		TRAM1_HUMAN (1-374): 7.57e-142: 409: 100.00