HitPredict

Interactor 1: RD23B (P54727)
UV excision repair protein RAD23 homolog B (HR23B) (hHR23B) (XP-C repair-complementing complex 58 kDa protein) (p58)
Gene: RAD23B

Interactor 2: PSMD1 (Q99460)
26S proteasome non-ATPase regulatory subunit 1 (26S proteasome regulatory subunit RPN2) (26S proteasome regulatory subunit S1) (26S proteasome subunit p112)
Gene: PSMD1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.776

Property	Details
Experiments	27114451, 16712842
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PC_rep~ubiquitin
Common GO terms	GO:0000502 - proteasome complex GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 409 Hs			1 953
+	Rn
		292215 RD23B_RAT (1-409): 1.14e-120: 358: 87.23		PSMD1_RAT (1-953): 0: 1304: 98.64
+	Hs
		872202 RD23A_HUMAN (1-409): 9.12e-94: 287: 56.72		PSMD1_HUMAN (1-953): 0: 1310: 100.00
+	Hs
		1303954 UBQL1_HUMAN (1-404): 1.25e-57: 200: 13.72		PSMD1_HUMAN (1-953): 0: 1310: 100.00
+	Hs
		1303948 UBQL2_HUMAN (1-364): 5.93e-51: 182: 13.68		PSMD1_HUMAN (1-953): 0: 1310: 100.00
+	Hs
		1303937 UBQL4_HUMAN (1-364): 2.75e-45: 166: 12.71		PSMD1_HUMAN (1-953): 0: 1310: 100.00
+	Mm
		476785 UBC_MOUSE (1-118): 1.78e-32: 131: 21.67		PSMD1_MOUSE (1-953): 0: 1308: 99.06
+	At
		221381 UBQ3_ARATH (1-80): 7.66e-29: 116: 28.75		PSD1A_ARATH (1-950): 0: 1219: 48.81
+	Dm
		1359018 Q9VWD9_DROME (1-353): 1.07e-44: 164: 11.08		PSMD1_DROME (2-933): 0: 1114: 61.64
+	Sc
		693266 RAD23_YEAST (1-407): 2.12e-72: 233: 28.41		RPN2_YEAST (2-953): 0: 984: 40.26
+	Hs
		872262 RD23B_HUMAN (1-409): 1.31e-125: 370: 100.00		PSMD2_HUMAN (8-796): 0: 802: 18.73
+	Rn
		1116239 RD23B_RAT (1-409): 1.14e-120: 358: 87.23		PSMD2_RAT (8-796): 0: 800: 18.73
+	Hs
		872151 RD23A_HUMAN (1-409): 9.12e-94: 287: 56.72		PSMD2_HUMAN (8-796): 0: 802: 18.73
+	At
		1195577 RD23C_ARATH (1-409): 1.9e-108: 327: 35.45		PSD2A_ARATH (8-796): 0: 738: 17.61
+	Hs
		1027821 UBQL1_HUMAN (1-404): 1.25e-57: 200: 13.72		PSMD2_HUMAN (8-796): 0: 802: 18.73
+	Hs
		1027815 UBQL2_HUMAN (1-364): 5.93e-51: 182: 13.68		PSMD2_HUMAN (8-796): 0: 802: 18.73
+	Hs
		1027806 UBQL4_HUMAN (1-364): 2.75e-45: 166: 12.71		PSMD2_HUMAN (8-796): 0: 802: 18.73
+	Mm
		476933 UBC_MOUSE (1-118): 1.78e-32: 131: 21.67		PSMD2_MOUSE (8-796): 0: 800: 18.73
+	Sp
		251964 RHP23_SCHPO (1-409): 1.78e-77: 245: 34.43		RPN1_SCHPO (8-794): 0: 666: 18.03
+	Dm
		1374998 Q9VWD9_DROME (1-353): 1.07e-44: 164: 11.08		Q9VW54_DROME (12-796): 0: 702: 16.86
+	Sc
		697080 RAD23_YEAST (1-407): 2.12e-72: 233: 28.41		RPN1_YEAST (8-604): 4.59e-149: 468: 15.96