HitPredict

Interactor 1: HDAC1 (O09106)
Histone deacetylase 1 (HD1) (EC 3.5.1.98) (Protein deacetylase HDAC1) (EC 3.5.1.-) (Protein deacylase HDAC1) (EC 3.5.1.-)
Gene: HDAC1

Interactor 2: SOX2 (P48432)
Transcription factor SOX-2
Gene: SOX2

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.80 0.60 0.694

The method score is based on:

Property Details
Experiments 21321941, 31077711, 21103394, 19139101
Identification Methods pull down, affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000976 - transcription cis-regulatory region binding
GO:0003677 - DNA binding
GO:0003682 - chromatin binding
and 9 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 482
Mm

1 319
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Service provided by Combinatics, Japan

Last updated: 11Aug2025