HitPredict

Interactor 1: EPHA4 (P54764)
Ephrin type-A receptor 4 (EC 2.7.10.1) (EPH-like kinase 8) (EK8) (hEK8) (Tyrosine-protein kinase TYRO1) (Tyrosine-protein kinase receptor SEK)
Gene: EPHA4

Interactor 2: LIN7C (Q9NUP9)
Protein lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3)
Gene: LIN7C

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~fn3
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0098839 - postsynaptic density membrane GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 986 Hs			1 197
+	Hs
		159179 EPHA4_HUMAN (1-986): 0: 1293: 100.00		CSKP_HUMAN (13-194): 1.3e-30: 119: 20.53
+	Hs
		1072612 EPHA7_HUMAN (5-986): 0: 1212: 62.37		LIN7C_HUMAN (1-197): 1.38e-57: 181: 100.00
+	Hs
		872639 EPHA4_HUMAN (1-986): 0: 1293: 100.00		DLG1_HUMAN (50-178): 8.31e-23: 97.1: 30.60
+	Hs
		872496 EPHA5_HUMAN (2-986): 0: 1201: 63.67		LIN7C_HUMAN (1-197): 1.38e-57: 181: 100.00
+	Hs
		872678 EPHA4_HUMAN (1-986): 0: 1293: 100.00		LNX1_HUMAN (14-179): 1.21e-17: 82.1: 22.02
+	Hs
		872638 EPHA4_HUMAN (1-986): 0: 1293: 100.00		PTN13_HUMAN (23-196): 2.66e-14: 72.5: 19.43
+	Hs
		872713 EPHA4_HUMAN (1-986): 0: 1293: 100.00		GOPC_HUMAN (92-173): 2.58e-13: 69.3: 46.34
+	Hs
		1072518 EPHA7_HUMAN (5-986): 0: 1212: 62.37		MPP7_HUMAN (31-188): 6.36e-31: 119: 25.95
+	Hs
		159214 EPHA7_HUMAN (5-986): 0: 1212: 62.37		CSKP_HUMAN (13-194): 1.3e-30: 119: 20.53
+	Hs
		1021499 EPHA7_HUMAN (5-986): 0: 1212: 62.37		DLG1_HUMAN (50-178): 8.31e-23: 97.1: 30.60
+	Hs
		872433 EPHA5_HUMAN (2-986): 0: 1201: 63.67		DLG1_HUMAN (50-178): 8.31e-23: 97.1: 30.60
+	Hs
		1072558 EPHA7_HUMAN (5-986): 0: 1212: 62.37		LNX1_HUMAN (14-179): 1.21e-17: 82.1: 22.02
+	Hs
		1020163 EPHA7_HUMAN (5-986): 0: 1212: 62.37		PTN13_HUMAN (23-196): 2.66e-14: 72.5: 19.43
+	Hs
		1072604 EPHA7_HUMAN (5-986): 0: 1212: 62.37		GOPC_HUMAN (92-173): 2.58e-13: 69.3: 46.34
+	Hs
		1072516 EPHA7_HUMAN (5-986): 0: 1212: 62.37		PDZ11_HUMAN (91-175): 4.41e-13: 65.5: 45.35
+	Hs
		872431 EPHA5_HUMAN (2-986): 0: 1201: 63.67		PTN13_HUMAN (23-196): 2.66e-14: 72.5: 19.43
+	Hs
		872493 EPHA5_HUMAN (2-986): 0: 1201: 63.67		GOPC_HUMAN (92-173): 2.58e-13: 69.3: 46.34
+	Hs
		872448 EPHA5_HUMAN (2-986): 0: 1201: 63.67		PDZ11_HUMAN (91-175): 4.41e-13: 65.5: 45.35
+	Hs
		665393 EPHA3_HUMAN (26-986): 0: 1182: 63.01		PTN13_HUMAN (23-196): 2.66e-14: 72.5: 19.43
+	Hs
		665403 EPHA3_HUMAN (26-986): 0: 1182: 63.01		PDZ11_HUMAN (91-175): 4.41e-13: 65.5: 45.35