HitPredict

Interactor 1: AFAD (P55196)
Afadin (ALL1-fused gene from chromosome 6 protein) (Protein AF-6) (Afadin adherens junction formation factor)
Gene: AFDN

Interactor 2: PKHA1 (Q9HB21)
Pleckstrin homology domain-containing family A member 1 (PH domain-containing family A member 1) (Tandem PH domain-containing protein 1) (TAPP-1)
Gene: PLEKHA1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	FHA~PH, PH~RA
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1824 Hs			1 404
+	Hs
		876417 AFAD_HUMAN (1-1824): 0: 1279: 100.00		PKHA7_HUMAN (105-397): 1.16e-33: 135: 17.24
+	Hs
		876505 AFAD_HUMAN (1-1824): 0: 1279: 100.00		PKHA5_HUMAN (130-342): 3.73e-33: 133: 20.55
+	Hs
		1020219 PTN13_HUMAN (978-1122): 1.17e-17: 92.2: 29.14		PKHA1_HUMAN (1-404): 6.66e-121: 358: 100.00
+	Hs
		1077289 DLG2_HUMAN (936-1143): 2.64e-33: 142: 24.55		PKHA2_HUMAN (1-404): 4.67e-100: 305: 43.52
+	Hs
		280075 MPDZ_HUMAN (971-1166): 2.25e-13: 78.3: 21.43		PKHA1_HUMAN (1-404): 6.66e-121: 358: 100.00
+	Hs
		1271029 DLG3_HUMAN (1009-1467): 4.67e-23: 109: 13.25		PKHA2_HUMAN (1-404): 4.67e-100: 305: 43.52
+	Ce
		619836 UN104_CAEEL (183-614): 6.37e-75: 279: 16.34		UN104_CAEEL (15-315): 2.43e-33: 134: 16.07
+	Hs
		1066395 KIF14_HUMAN (179-624): 8.03e-59: 227: 18.67		AFAP1_HUMAN (6-309): 5.13e-47: 173: 14.46
+	Hs
		1020218 PTN13_HUMAN (978-1122): 1.17e-17: 92.2: 29.14		PKHA2_HUMAN (1-404): 4.67e-100: 305: 43.52
+	Hs
		1153398 KI13B_HUMAN (184-691): 5.1e-66: 250: 12.64		PKHA7_HUMAN (105-397): 1.16e-33: 135: 17.24
+	Hs
		280074 MPDZ_HUMAN (971-1166): 2.25e-13: 78.3: 21.43		PKHA2_HUMAN (1-404): 4.67e-100: 305: 43.52
+	Hs
		1334844 KI13B_HUMAN (184-691): 5.1e-66: 250: 12.64		PKHA5_HUMAN (130-342): 3.73e-33: 133: 20.55
+	Hs
		212312 KIF14_HUMAN (179-624): 8.03e-59: 227: 18.67		CYH3_HUMAN (193-289): 5.3e-32: 126: 25.83
+	Hs
		1066158 KIF14_HUMAN (179-624): 8.03e-59: 227: 18.67		CYH1_HUMAN (193-289): 1.23e-30: 123: 25.83
+	Hs
		1066465 KIF14_HUMAN (179-624): 8.03e-59: 227: 18.67		ARAP2_HUMAN (210-301): 1.82e-11: 68.1: 14.74
+	Hs
		1066291 KIF14_HUMAN (179-624): 8.03e-59: 227: 18.67		MPRIP_HUMAN (203-403): 2.81e-10: 64.3: 16.26
+	Hs
		1066936 KIF14_HUMAN (179-624): 8.03e-59: 227: 18.67		FARP1_HUMAN (29-347): 7e-10: 63.1: 13.04
+	Mm
		140105 DLG4_MOUSE (1002-1238): 8.46e-28: 123: 17.51		CYH3_MOUSE (193-289): 1.42e-33: 131: 26.05
+	Hs
		1234150 MYO5C_HUMAN (1345-1816): 2.22e-12: 75: 9.60		AFAP1_HUMAN (6-309): 5.13e-47: 173: 14.46
+	Mm
		926281 DLG4_MOUSE (1002-1238): 8.46e-28: 123: 17.51		CYH2_MOUSE (193-290): 4.92e-31: 124: 24.79