HitPredict

Interactor 1: RGS2 (P49808)
Regulator of G-protein signaling rgs-2
Gene: rgs-2

Interactor 2: GNAO (P51875)
Guanine nucleotide-binding protein G(o) subunit alpha
Gene: goa-1

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.80	0.579

Property	Details
Experiments	10950865
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	G-alpha~RGS
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 169 Ce			1 354
+	Hs
		303102 RGS20_HUMAN (15-166): 5.02e-64: 202: 57.24		GNAO_HUMAN (1-354): 1.2e-174: 490: 82.20
+	Hs
		303125 RGS20_HUMAN (15-166): 5.02e-64: 202: 57.24		GNAI1_HUMAN (1-354): 1.97e-172: 485: 69.86
+	Hs
		418623 RGS3_HUMAN (13-165): 5.62e-61: 205: 35.29		GNAI2_HUMAN (1-354): 2.24e-171: 482: 68.17
+	Hs
		303098 RGS20_HUMAN (15-166): 5.02e-64: 202: 57.24		GNAI2_HUMAN (1-354): 2.24e-171: 482: 68.17
+	Hs
		475923 RGS3_HUMAN (13-165): 5.62e-61: 205: 35.29		GNAI3_HUMAN (1-354): 1.74e-169: 477: 69.86
+	Hs
		297293 RGS9_HUMAN (16-168): 4.33e-56: 188: 32.68		GNAO_HUMAN (1-354): 1.2e-174: 490: 82.20
+	Hs
		482588 RGS19_HUMAN (13-168): 3.31e-60: 187: 53.21		GNAO_HUMAN (1-354): 1.2e-174: 490: 82.20
+	Hs
		989889 RGS17_HUMAN (8-167): 5.65e-61: 189: 51.25		GNAI1_HUMAN (1-354): 1.97e-172: 485: 69.86
+	Hs
		890627 RGS19_HUMAN (13-168): 3.31e-60: 187: 53.21		GNAI1_HUMAN (1-354): 1.97e-172: 485: 69.86
+	Ce
		758617 RGS1_CAEEL (1-169): 3.46e-61: 189: 64.50		GNAO_CAEEL (1-354): 3.14e-171: 482: 100.00
+	Hs
		220444 RGS14_HUMAN (2-164): 1.24e-55: 185: 29.59		GNAI1_HUMAN (1-354): 1.97e-172: 485: 69.86
+	Hs
		418622 RGS19_HUMAN (13-168): 3.31e-60: 187: 53.21		GNAI2_HUMAN (1-354): 2.24e-171: 482: 68.17
+	Hs
		220432 RGS14_HUMAN (2-164): 1.24e-55: 185: 29.59		GNAI2_HUMAN (1-354): 2.24e-171: 482: 68.17
+	Hs
		476055 RGS17_HUMAN (8-167): 5.65e-61: 189: 51.25		GNAI3_HUMAN (1-354): 1.74e-169: 477: 69.86
+	Hs
		475922 RGS19_HUMAN (13-168): 3.31e-60: 187: 53.21		GNAI3_HUMAN (1-354): 1.74e-169: 477: 69.86
+	Hs
		220434 RGS14_HUMAN (2-164): 1.24e-55: 185: 29.59		GNAI3_HUMAN (1-354): 1.74e-169: 477: 69.86
+	Hs
		715999 RGS3_HUMAN (13-165): 5.62e-61: 205: 35.29		GNA11_HUMAN (1-353): 7.39e-159: 450: 48.02
+	Hs
		303104 RGS20_HUMAN (15-166): 5.02e-64: 202: 57.24		GNAZ_HUMAN (1-353): 1.08e-154: 440: 59.89
+	Hs
		220438 RGS14_HUMAN (2-164): 1.24e-55: 185: 29.59		GNA11_HUMAN (1-353): 7.39e-159: 450: 48.02
+	Hs
		618441 RGS19_HUMAN (13-168): 3.31e-60: 187: 53.21		GNAZ_HUMAN (1-353): 1.08e-154: 440: 59.89