HitPredict

Interactor 1: PTEN (P60484)
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (EC 3.1.3.16) (EC 3.1.3.48) (EC 3.1.3.67) (Inositol polyphosphate 3-phosphatase) (EC 3.1.3.-) (Mutated in multiple advanced cancers 1) (Phosphatase and tensin homolog)
Gene: PTEN

Interactor 2: MPRIP (Q6WCQ1)
Myosin phosphatase Rho-interacting protein (M-RIP) (Rho-interacting protein 3) (RIP3) (p116Rip)
Gene: MPRIP

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.63	0.60	0.619

Property	Details
Experiments	26561776, 21653829
Identification Methods	pull down, two hybrid, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 403 Hs			1 1025
+	Hs
		725123 PTEN_HUMAN (1-403): 4.63e-168: 478: 100.00		MYH10_HUMAN (534-1014): 3.94e-16: 85.9: 9.18
+	Hs
		890672 PTEN_HUMAN (1-403): 4.63e-168: 478: 100.00		PLEC_HUMAN (499-978): 3.1e-11: 70.1: 14.96
+	Hs
		161674 GAK_HUMAN (22-402): 1.74e-116: 370: 23.39		PKHA7_HUMAN (336-980): 5.04e-41: 166: 13.51
+	Hs
		161596 GAK_HUMAN (22-402): 1.74e-116: 370: 23.39		HIP1R_HUMAN (626-929): 1.25e-09: 64.5: 19.56
+	Hs
		1153452 CC14A_HUMAN (17-176): 1.42e-36: 142: 19.16		PKHA7_HUMAN (336-980): 5.04e-41: 166: 13.51