Interactor 1: RAB10 (P61026)
Ras-related protein Rab-10 (EC 3.6.5.2)
Gene: RAB10

Interactor 2: LRRK2 (Q5S007)
Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin)
Gene: LRRK2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.73 1.00 0.857

The method score is based on:

Property Details
Experiments 31046837, 26824392, unassigned1853
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, protein kinase assay
Interaction Type physical association, association, phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Ras, Ras~Roc
Common GO terms GO:0000139 - Golgi membrane
GO:0005525 - GTP binding
GO:0005768 - endosome
GO:0005789 - endoplasmic reticulum membrane
GO:0005794 - Golgi apparatus
and 5 others

more...

Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 200
Hs

1 2527
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Last updated: 15 Jul 2024