HitPredict

Interactor 1: RAB10 (P61026)
Ras-related protein Rab-10 (EC 3.6.5.2)
Gene: RAB10

Interactor 2: RB39A (Q14964)
Ras-related protein Rab-39A (Rab-39)
Gene: RAB39A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.57	1.00	0.759

Property	Details
Experiments	30021884, 26824392
Identification Methods	proximity labelling technology, anti tag coimmunoprecipitation, cross-linking study
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ras~Ras
Common GO terms	GO:0000139 - Golgi membrane GO:0005525 - GTP binding GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0016192 - vesicle-mediated transport and 1 others more... GO:0030670 - phagocytic vesicle membrane
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 200 Hs			1 217
+	Hs
		895217 RAB8B_HUMAN (1-198): 2.21e-100: 290: 70.20		RAB2A_HUMAN (5-196): 2.86e-89: 263: 48.96
+	Hs
		1273009 RAB8B_HUMAN (1-198): 2.21e-100: 290: 70.20		RAB1B_HUMAN (1-217): 9.76e-83: 246: 39.63
+	Hs
		894734 RAB8A_HUMAN (1-199): 1.02e-96: 281: 67.32		RB39A_HUMAN (1-217): 4.32e-84: 250: 100.00
+	Hs
		894715 RAB8A_HUMAN (1-199): 1.02e-96: 281: 67.32		RAB1A_HUMAN (1-217): 2.09e-83: 248: 41.01
+	Hs
		894712 RAB8A_HUMAN (1-199): 1.02e-96: 281: 67.32		RB11A_HUMAN (2-216): 2.76e-81: 243: 38.14
+	Hs
		895549 RAB10_HUMAN (1-200): 3.02e-89: 262: 100.00		RAB1B_HUMAN (1-217): 9.76e-83: 246: 39.63
+	Mm
		895587 RAB10_MOUSE (1-200): 3.02e-89: 262: 100.00		RAB1B_MOUSE (1-217): 1.09e-82: 246: 39.63
+	Mm
		877197 RAB8A_MOUSE (4-181): 5.12e-93: 271: 75.98		RB39B_MOUSE (1-217): 1.1e-78: 236: 76.04
+	Hs
		895472 RAB10_HUMAN (1-200): 3.02e-89: 262: 100.00		RB11A_HUMAN (2-216): 2.76e-81: 243: 38.14
+	Hs
		895532 RAB10_HUMAN (1-200): 3.02e-89: 262: 100.00		RAB1C_HUMAN (1-217): 1.09e-79: 238: 37.79
+	Mm
		895581 RAB10_MOUSE (1-200): 3.02e-89: 262: 100.00		RB39B_MOUSE (1-217): 1.1e-78: 236: 76.04
+	Mm
		877189 RAB8B_MOUSE (1-198): 3.07e-100: 290: 70.20		RAB8A_MOUSE (1-175): 3.95e-51: 166: 46.29
+	Hs
		894787 RAB8B_HUMAN (1-198): 2.21e-100: 290: 70.20		RAB8A_HUMAN (1-175): 2.4e-51: 166: 46.29
+	Hs
		845875 RAB8B_HUMAN (1-198): 2.21e-100: 290: 70.20		RAB13_HUMAN (1-182): 2.76e-50: 164: 45.06
+	Hs
		845844 RAB8A_HUMAN (1-199): 1.02e-96: 281: 67.32		RAB13_HUMAN (1-182): 2.76e-50: 164: 45.06
+	Mm
		877188 RAB10_MOUSE (1-200): 3.02e-89: 262: 100.00		RAB8A_MOUSE (1-175): 3.95e-51: 166: 46.29
+	Hs
		894709 RAB10_HUMAN (1-200): 3.02e-89: 262: 100.00		RAB8A_HUMAN (1-175): 2.4e-51: 166: 46.29
+	Mm
		895589 RAB10_MOUSE (1-200): 3.02e-89: 262: 100.00		RAB13_MOUSE (1-182): 8.75e-51: 165: 46.70