HitPredict

Interactor 1: WDR5 (P61964)
WD repeat-containing protein 5 (BMP2-induced 3-kb gene protein)
Gene: WDR5

Interactor 2: NUP43 (Q8NFH3)
Nucleoporin Nup43 (Nup107-160 subcomplex subunit Nup43) (p42)
Gene: NUP43

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	37689310
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	WD40~WD40
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 334 Hs			1 380
+	Hs
		903418 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		FBXW7_HUMAN (3-371): 2.85e-70: 235: 12.30
+	Hs
		903077 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		WDR5_HUMAN (3-289): 4.3e-58: 193: 14.24
+	Hs
		903471 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		GRWD1_HUMAN (68-330): 6.16e-56: 191: 15.84
+	Hs
		792949 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		LIS1_HUMAN (5-248): 1.25e-48: 171: 12.06
+	Dm
		1358859 WDS_DROME (3-290): 7.53e-92: 279: 31.21		FBXW7_DROME (102-377): 2.21e-60: 212: 14.80
+	Hs
		903428 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		SNR40_HUMAN (249-378): 1.1e-25: 107: 17.04
+	Hs
		196984 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		PRP4_HUMAN (215-379): 1.68e-23: 103: 17.71
+	Hs
		903171 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		RBBP4_HUMAN (216-378): 3.53e-19: 90.3: 13.59
+	Hs
		209416 PLRG1_HUMAN (2-333): 5.29e-85: 267: 26.05		WDR5_HUMAN (3-289): 4.3e-58: 193: 14.24
+	Hs
		792935 LIS1_HUMAN (2-289): 1.55e-94: 288: 29.49		LIS1_HUMAN (5-248): 1.25e-48: 171: 12.06
+	Mm
		925836 LIS1_MOUSE (2-289): 1.02e-94: 288: 29.49		LIS1_MOUSE (5-248): 8.59e-49: 171: 12.06
+	Hs
		1240442 POC1B_HUMAN (5-251): 5.05e-84: 263: 27.89		POC1A_HUMAN (159-379): 2.9e-54: 185: 16.52
+	Hs
		903349 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		WDR5B_HUMAN (293-379): 3.07e-12: 68.7: 13.33
+	Hs
		903551 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		NLE1_HUMAN (3-100): 1.12e-09: 61.7: 9.09
+	Dm
		1358845 WDS_DROME (3-290): 7.53e-92: 279: 31.21		WDS_DROME (255-379): 3.32e-27: 112: 19.53
+	Hs
		209467 PLRG1_HUMAN (2-333): 5.29e-85: 267: 26.05		SNR40_HUMAN (249-378): 1.1e-25: 107: 17.04
+	Hs
		1288273 WDR83_HUMAN (25-333): 8.76e-84: 257: 31.83		SNR40_HUMAN (249-378): 1.1e-25: 107: 17.04
+	Ce
		954090 LIS1_CAEEL (2-289): 8.81e-87: 268: 24.68		LIN53_CAEEL (216-378): 1.44e-20: 94.1: 14.29