Interactor 1: PURT (P33221)
Formate-dependent phosphoribosylglycinamide formyltransferase (EC 6.3.1.21) (5'-phosphoribosylglycinamide transformylase 2) (Formate-dependent GAR transformylase) (GAR transformylase 2) (GART 2) (GAR transformylase T) (Non-folate glycinamide ribonucleotide transformylase) (Phosphoribosylglycinamide formyltransferase 2)
Gene: PURT

Interactor 2: PURT (P33221)
Formate-dependent phosphoribosylglycinamide formyltransferase (EC 6.3.1.21) (5'-phosphoribosylglycinamide transformylase 2) (Formate-dependent GAR transformylase) (GAR transformylase 2) (GART 2) (GAR transformylase T) (Non-folate glycinamide ribonucleotide transformylase) (Phosphoribosylglycinamide formyltransferase 2)
Gene: PURT

Species: Escherichia coli K-12

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.48 1.00 0.698

The method score is based on:

Property Details
Experiments 24561554
Identification Methods two hybrid, two hybrid array
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains ATP-grasp~ATP-grasp
Common GO terms GO:0000287 - magnesium ion binding
GO:0004644 - phosphoribosylglycinamide formyltransferase activity
GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0006189 - 'de novo' IMP biosynthetic process
and 3 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 392
Ec

1 392
+ Hs
+ Hs
+ Sc
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Sc
+ Hs
+ Ec
+ Hs
+ Sc
+ Dm

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Last updated: 15 Jul 2024