HitPredict

Interactor 1: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Interactor 2: KC1G3 (Q9Y6M4)
Casein kinase I isoform gamma-3 (CKI-gamma 3) (EC 2.7.11.1)
Gene: CSNK1G3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	34079125, 31871319
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~Ras
Common GO terms	GO:0005634 - nucleus GO:0005886 - plasma membrane GO:0007165 - signal transduction
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 196 Hs			1 447
+	Hs
		925773 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		KC1G3_HUMAN (1-447): 2.1e-138: 406: 100.00
+	Hs
		901107 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		KC1G3_HUMAN (1-447): 2.1e-138: 406: 100.00
+	Hs
		545731 RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57		KC1G3_HUMAN (1-447): 2.1e-138: 406: 100.00
+	Hs
		436599 RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16		KC1G3_HUMAN (1-447): 2.1e-138: 406: 100.00
+	Hs
		951505 RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53		KC1G3_HUMAN (1-447): 2.1e-138: 406: 100.00
+	Hs
		892707 RAC3_HUMAN (1-179): 1.15e-74: 224: 57.54		KC1G3_HUMAN (1-447): 2.1e-138: 406: 100.00
+	Hs
		894641 CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49		KC1G3_HUMAN (1-447): 2.1e-138: 406: 100.00
+	Hs
		821977 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		KC1A_HUMAN (28-364): 3.67e-130: 381: 50.59
+	Hs
		564761 RHOQ_HUMAN (2-195): 6.71e-68: 207: 51.74		KC1G3_HUMAN (1-447): 2.1e-138: 406: 100.00
+	Hs
		821973 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		KC1A_HUMAN (28-364): 3.67e-130: 381: 50.59
+	Hs
		120742 RHOD_HUMAN (7-182): 3.37e-66: 203: 53.98		KC1G3_HUMAN (1-447): 2.1e-138: 406: 100.00
+	Hs
		681775 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		AKT1_HUMAN (4-386): 2.58e-122: 366: 19.74
+	Hs
		568619 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		KAPCA_HUMAN (6-370): 6.92e-123: 363: 19.95
+	Hs
		623871 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		KPCL_HUMAN (3-384): 2.51e-120: 367: 15.72
+	Hs
		568611 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		KAPCA_HUMAN (6-370): 6.92e-123: 363: 19.95
+	Hs
		545209 RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57		KAPCB_HUMAN (2-367): 3.04e-122: 361: 20.43
+	Hs
		436148 RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16		KAPCA_HUMAN (6-370): 6.92e-123: 363: 19.95
+	Hs
		568605 CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49		KAPCA_HUMAN (6-370): 6.92e-123: 363: 19.95
+	Hs
		564425 RHOQ_HUMAN (2-195): 6.71e-68: 207: 51.74		AKT2_HUMAN (1-386): 6.22e-125: 373: 18.37