HitPredict

Interactor 1: H4 (P62805)
Histone H4
Gene: H4C1

Interactor 2: BRD3 (Q15059)
Bromodomain-containing protein 3 (RING3-like protein)
Gene: BRD3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.76	0.60	0.676

Property	Details
Experiments	27248496, 30804502, 30554943, 34349018
Identification Methods	affinity chromatography technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 103 Hs			1 726
+	Hs
		631388 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		BRD2_HUMAN (5-700): 1.46e-129: 405: 58.08
+	Mm
		918262 H4_MOUSE (1-103): 1.38e-48: 151: 100.00		BRDT_MOUSE (12-718): 2.35e-104: 342: 47.24
+	Hs
		918130 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		ZMYD8_HUMAN (3-725): 8.92e-52: 196: 12.21
+	Hs
		917307 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		ZMY11_HUMAN (3-446): 1.03e-44: 171: 9.63
+	Zm
		19319 A0A1D6IAU4_MAIZE (1-103): 4.97e-53: 163: 98.06		A0A1D6HCG5_MAIZE (18-310): 2.04e-33: 139: 17.41
+	Hs
		917170 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		EP300_HUMAN (4-177): 1.2e-34: 144: 22.86
+	Hs
		917688 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		KAT2A_HUMAN (267-414): 1.15e-33: 140: 28.86
+	Hs
		917689 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		KAT2B_HUMAN (267-414): 8.8e-32: 134: 25.50
+	Dm
		532730 H4_DROME (1-103): 4.51e-48: 150: 99.03		FSH_DROME (277-481): 4.78e-28: 123: 26.21
+	Hs
		876684 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		BRPF1_HUMAN (20-274): 6.8e-26: 116: 14.94
+	Sp
		448927 H4_SCHPO (18-103): 4.87e-42: 135: 89.54		YK82_SCHPO (29-148): 6.59e-30: 128: 33.61
+	Dm
		950390 H4_DROME (1-103): 4.51e-48: 150: 99.03		Q4V5A7_DROME (288-482): 3.65e-25: 113: 23.08
+	Hs
		244235 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		BRD4_HUMAN (273-605): 9.08e-20: 96.8: 17.56
+	Dm
		950405 H4_DROME (1-103): 4.51e-48: 150: 99.03		Q9VCG6_DROME (273-565): 1.87e-20: 97.6: 15.36
+	Hs
		917657 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		PHIP_HUMAN (5-708): 5.37e-19: 94.5: 10.37
+	Hs
		917517 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		PB1_HUMAN (152-650): 1.14e-18: 93.3: 11.68
+	Hs
		917576 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		TAF1L_HUMAN (24-303): 9.96e-18: 90.3: 13.57
+	Hs
		600119 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		TAF1_HUMAN (23-303): 3.47e-17: 88.7: 13.52
+	Dm
		950422 H4_DROME (1-103): 4.51e-48: 150: 99.03		NU301_DROME (36-137): 3.14e-12: 72.4: 38.24
+	Sp
		448934 H4_SCHPO (18-103): 4.87e-42: 135: 89.54		GCN5_SCHPO (331-412): 7.79e-09: 60.5: 32.93