Interactor 1: PLK1 (P53350)
Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13)
Gene: PLK1
Interactor 2: NOTC2 (Q04721)
Neurogenic locus notch homolog protein 2 (Notch 2) (hN2) [Cleaved into: Notch 2 extracellular truncation (N2ECD); Notch 2 intracellular domain (N2ICD)]
Gene: NOTCH2
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.33 | 1.00 | 0.575 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | unassigned3799 |
| Identification Methods | anti tag coimmunoprecipitation |
| Interaction Type | association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Ank~Pkinase, Ank_2~Pkinase |
| Common GO terms | GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0043066 - negative regulation of apoptotic process |
| Homologous interactions | 11 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
