Interactor 1: HST2 (P53686)
NAD-dependent protein deacetylase HST2 (EC 2.3.1.286) (Homologous to SIR2 protein 2) (Regulatory protein SIR2 homolog 2)
Gene: HST2

Interactor 2: HST2 (P53686)
NAD-dependent protein deacetylase HST2 (EC 2.3.1.286) (Homologous to SIR2 protein 2) (Regulatory protein SIR2 homolog 2)
Gene: HST2

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 33187982
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains SIR2~SIR2
Common GO terms GO:0000183 - rDNA heterochromatin formation
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0017136 - histone deacetylase activity, NAD-dependent
GO:0045950 - negative regulation of mitotic recombination
and 3 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 357
Sc

1 357
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Sc
+ Hs
+ Sc
+ Hs
+ Mm
+ Sc
+ Ec
+ Hp

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Last updated: 11Aug2025