HitPredict

Interactor 1: SIR5 (Q8K2C6)
NAD-dependent protein deacylase sirtuin-5, mitochondrial (EC 2.3.1.-) (Regulatory protein SIR2 homolog 5) (SIR2-like protein 5)
Gene: Sirt5

Interactor 2: SIR5 (Q8K2C6)
NAD-dependent protein deacylase sirtuin-5, mitochondrial (EC 2.3.1.-) (Regulatory protein SIR2 homolog 5) (SIR2-like protein 5)
Gene: Sirt5

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.68 1.00 0.827

The method score is based on:

Property Details
Experiments 29199018, 29222160, 28130547
Identification Methods cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains SIR2~SIR2
Common GO terms GO:0002931 - response to ischemia
GO:0005634 - nucleus
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0005758 - mitochondrial intermembrane space
and 17 others

more...
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 310
Mm

1 310
+ Hs
+ Hs
+ Hs
+ Sc
+ Hs
+ Hs
+ Hs
+ Hs
+ Ec
+ Sc
+ Sc
+ Hp
+ Sc

Service provided by Combinatics, Japan

Last updated: 11Aug2025