HitPredict

Interactor 1: BLM (P54132)
RecQ-like DNA helicase BLM (EC 5.6.2.4) (Bloom syndrome protein) (DNA 3'-5' helicase BLM) (DNA helicase, RecQ-like type 2) (RecQ2) (RecQ protein-like 3)
Gene: BLM

Interactor 2: UTP4 (Q969X6)
U3 small nucleolar RNA-associated protein 4 homolog (Cirhin) (UTP4 small subunit processome component)
Gene: UTP4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Helicase_C~WD40
Common GO terms	GO:0005654 - nucleoplasm GO:0005694 - chromosome GO:0005730 - nucleolus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1417 Hs			1 686
+	Hs
		926401 BLM_HUMAN (1-1417): 0: 904: 100.00		TEP1_HUMAN (360-675): 5.32e-25: 113: 9.49
+	Hs
		926419 BLM_HUMAN (1-1417): 0: 904: 100.00		NLE1_HUMAN (1-86): 4.27e-19: 93: 14.94
+	Hs
		926395 BLM_HUMAN (1-1417): 0: 904: 100.00		SNR40_HUMAN (518-609): 1.38e-09: 62.3: 8.70
+	Hs
		1122945 WRN_HUMAN (487-1294): 1.8e-143: 477: 23.02		UTP4_HUMAN (1-686): 1.83e-144: 438: 99.13
+	Hs
		193136 DDX3Y_HUMAN (479-1052): 7.39e-127: 410: 14.89		UTP4_HUMAN (1-686): 1.83e-144: 438: 99.13
+	Hs
		193129 DDX3Y_HUMAN (479-1052): 7.39e-127: 410: 14.89		POC1A_HUMAN (4-171): 5.19e-45: 167: 13.61
+	Hs
		1122946 WRN_HUMAN (487-1294): 1.8e-143: 477: 23.02		SNR40_HUMAN (518-609): 1.38e-09: 62.3: 8.70
+	Hs
		854929 RECQ1_HUMAN (627-1233): 4.42e-130: 419: 34.81		SKI8_HUMAN (98-315): 9.05e-19: 89.5: 15.77
+	Hs
		316325 RECQ5_HUMAN (648-1407): 1.01e-123: 412: 26.81		NLE1_HUMAN (1-86): 4.27e-19: 93: 14.94
+	Hs
		1369406 DDX17_HUMAN (581-1080): 1.19e-119: 393: 19.11		NLE1_HUMAN (1-86): 4.27e-19: 93: 14.94
+	Hs
		141400 DDX3X_HUMAN (488-1052): 8.19e-130: 418: 15.36		WDR5_HUMAN (572-678): 8.98e-11: 65.7: 11.22
+	Hs
		316307 RECQ5_HUMAN (648-1407): 1.01e-123: 412: 26.81		SNR40_HUMAN (518-609): 1.38e-09: 62.3: 8.70
+	Hs
		608525 DDX5_HUMAN (551-1025): 7.7e-123: 398: 19.27		WDR5_HUMAN (572-678): 8.98e-11: 65.7: 11.22
+	Hs
		608695 DDX5_HUMAN (551-1025): 7.7e-123: 398: 19.27		SNR40_HUMAN (518-609): 1.38e-09: 62.3: 8.70
+	Hs
		965133 DDX17_HUMAN (581-1080): 1.19e-119: 393: 19.11		WDR5_HUMAN (572-678): 8.98e-11: 65.7: 11.22
+	Hs
		1369343 DDX17_HUMAN (581-1080): 1.19e-119: 393: 19.11		SNR40_HUMAN (518-609): 1.38e-09: 62.3: 8.70
+	Hs
		315745 RECQ4_HUMAN (661-1003): 2.21e-43: 175: 34.80		WDR5B_HUMAN (1-221): 5.66e-49: 176: 14.78
+	Hs
		315993 RECQ4_HUMAN (661-1003): 2.21e-43: 175: 34.80		SKI8_HUMAN (98-315): 9.05e-19: 89.5: 15.77
+	Hs
		315206 RECQ4_HUMAN (661-1003): 2.21e-43: 175: 34.80		COPB2_HUMAN (478-612): 7.14e-13: 74.2: 17.04
+	Hs
		315371 RECQ4_HUMAN (661-1003): 2.21e-43: 175: 34.80		WDR5_HUMAN (572-678): 8.98e-11: 65.7: 11.22