Protein: UTP4
U3 small nucleolar RNA-associated protein 4 homolog (Cirhin) (UTP4 small subunit processome component)

Gene: UTP4
Organism: Homo sapiens
Interactions: 195
UniProt ID: Q969X6

Gene Ontology (top 5):
GO:0000462 - maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0001650 - fibrillar center
GO:0003723 - RNA binding
GO:0005654 - nucleoplasm
GO:0005694 - chromosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1141403

WDR43
WD repeat-containing protein 43

7

20

Small-scale

0.962

High

1352435

UTP15
U3 small nucleolar RNA-associated protein 15 homolog

6

17

Small-scale

0.941

High

1381597

ANLN
Anillin

2

6

High-throughput

0.754

High

1381607

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

2

9

High-throughput

0.754

High

1381589

NOL11
Nucleolar protein 11

6

4

Small-scale

0.734

High

1309697

WDR75
WD repeat-containing protein 75

5

18

Small-scale

0.709

High

228736

U3IP2
U3 small nucleolar RNA-interacting protein 2

1

18

High-throughput

0.691

High

1099751

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

1

2

High-throughput

0.691

High

1381566

UTP4
U3 small nucleolar RNA-associated protein 4 homolog

1

18

High-throughput

0.691

High

177282

ANR28
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A

4

4

High-throughput

0.691

High

1351514

HAVR2
Hepatitis A virus cellular receptor 2

2

0

High-throughput

0.679

High

1105647

GOGA4
Golgin subfamily A member 4

3

20

High-throughput

0.667

High

1381614

UTP16
U3 small nucleolar RNA-associated protein NOL7

4

0

High-throughput

0.661

High

346161

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

3

15

High-throughput

0.640

High

193136

DDX3Y
ATP-dependent RNA helicase DDX3Y

1

8

High-throughput

0.618

High

907525

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

4

High-throughput

0.618

High

926391

BLM
RecQ-like DNA helicase BLM

1

20

High-throughput

0.618

High

980102

H4
Histone H4

1

6

High-throughput

0.618

High

998648

H31
Histone H3.1

1

11

High-throughput

0.618

High

1122945

WRN
Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN

1

20

High-throughput

0.618

High

1289516

NAA40
N-alpha-acetyltransferase 40

1

1

High-throughput

0.618

High

1381590

DDX31
ATP-dependent DNA helicase DDX31

1

14

High-throughput

0.618

High

1381620

UTP18
U3 small nucleolar RNA-associated protein 18 homolog

1

19

High-throughput

0.618

High

141036

NOP56
Nucleolar protein 56

2

10

High-throughput

0.611

High

447288

NPM
Nucleophosmin

2

9

High-throughput

0.611

High

1161591

IF16
Gamma-interferon-inducible protein 16

2

8

High-throughput

0.611

High

1381579

RBM4B
RNA-binding protein 4B

2

12

High-throughput

0.611

High

896602

VASP
Vasodilator-stimulated phosphoprotein

3

2

High-throughput

0.609

High

1331718

NECA1
N-terminal EF-hand calcium-binding protein 1

2

0

High-throughput

0.602

High

1104637

IKZF1
DNA-binding protein Ikaros

2

5

High-throughput

0.601

High

372774

MYC
Myc proto-oncogene protein

2

20

High-throughput

0.584

High

1381583

XRN2
5'-3' exoribonuclease 2

2

4

High-throughput

0.584

High

1208944

DCA10
DDB1- and CUL4-associated factor 10

1

17

High-throughput

0.575

High

1215344

DCAF8
DDB1- and CUL4-associated factor 8

1

18

High-throughput

0.575

High

396668

ESR1
Estrogen receptor

2

20

High-throughput

0.571

High

157708

CTRO
Citron Rho-interacting kinase

1

10

High-throughput

0.553

High

1254950

TRI67
Tripartite motif-containing protein 67

1

12

High-throughput

0.553

High

1381585

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.553

High

1381600

STRN4
Striatin-4

1

18

High-throughput

0.553

High

422801

A4
Amyloid-beta precursor protein

2

3

High-throughput

0.550

High

239165

ZNRD2
Protein ZNRD2

2

1

High-throughput

0.549

High

370750

FOS
Protein c-Fos

1

9

High-throughput

0.536

High

634564

LMNB1
Lamin-B1

1

10

High-throughput

0.536

High

1119072

C1D
Nuclear nucleic acid-binding protein C1D

1

2

High-throughput

0.536

High

1381577

MPH6
M-phase phosphoprotein 6

1

2

High-throughput

0.536

High

1381594

EXOS4
Exosome complex component RRP41

1

11

High-throughput

0.536

High

1381596

EXOS5
Exosome complex component RRP46

1

11

High-throughput

0.536

High

1381610

HDAC6
Protein deacetylase HDAC6

1

9

High-throughput

0.536

High

1154147

ITSN1
Intersectin-1

2

4

High-throughput

0.521

High

1242420

RHGBA
Rho GTPase-activating protein 11A

2

6

High-throughput

0.521

High

425596

ISG15
Ubiquitin-like protein ISG15

1

10

High-throughput

0.515

High

1200923

WDR81
WD repeat-containing protein 81

1

16

Small-scale

0.514

High

1381608

IKBL1
NF-kappa-B inhibitor-like protein 1

1

0

High-throughput

0.513

High

586333

ZEP1
Zinc finger protein 40

1

6

Small-scale

0.506

High

718445

CD6
T-cell differentiation antigen CD6

1

1

High-throughput

0.489

High

1057107

FMOD
Fibromodulin

1

2

High-throughput

0.489

High

1132625

KIF22
Kinesin-like protein KIF22

1

3

High-throughput

0.489

High

1243762

FXL19
F-box/LRR-repeat protein 19

1

4

High-throughput

0.489

High

1279120

GOGA7
Golgin subfamily A member 7

1

1

High-throughput

0.489

High

1349967

CERK1
Ceramide kinase

1

1

High-throughput

0.489

High

1381570

HDA11
Histone deacetylase 11

1

8

High-throughput

0.489

High

1381601

ANKE1
Ankyrin repeat and EF-hand domain-containing protein 1

1

5

High-throughput

0.489

High

1381612

EVL
Ena/VASP-like protein

1

2

High-throughput

0.489

High

1381617

KLH20
Kelch-like protein 20

1

4

High-throughput

0.489

High

1381575

DAA10
Dynein axonemal assembly factor 10

1

0

High-throughput

0.481

High

96737

E9PAV9
G patch domain-containing protein 4

1

4

High-throughput

0.479

High

138262

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

3

High-throughput

0.479

High

140616

MPP10
U3 small nucleolar ribonucleoprotein protein MPP10

1

4

High-throughput

0.479

High

173181

XPO1
Exportin-1

1

13

High-throughput

0.479

High

183049

NKRF
NF-kappa-B-repressing factor

1

3

High-throughput

0.479

High

187150

PPM1G
Protein phosphatase 1G

1

1

High-throughput

0.479

High

223240

PRC1
Protein regulator of cytokinesis 1

1

11

High-throughput

0.479

High

248029

NUPR1
Nuclear protein 1

1

5

High-throughput

0.479

High

291116

UTP20
Small subunit processome component 20 homolog

1

1

High-throughput

0.479

High

331214

KI20A
Kinesin-like protein KIF20A

1

20

High-throughput

0.479

High

406468

MYCN
N-myc proto-oncogene protein

1

20

High-throughput

0.479

High

414360

P53
Cellular tumor antigen p53

1

8

High-throughput

0.479

High

487614

PARP1
Poly [ADP-ribose] polymerase 1

1

7

High-throughput

0.479

High

589345

RFA2
Replication protein A 32 kDa subunit

1

7

High-throughput

0.479

High

604714

UBF1
Nucleolar transcription factor 1

1

16

High-throughput

0.479

High

639794

TAF1
Transcription initiation factor TFIID subunit 1

1

20

High-throughput

0.479

High

643968

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

6

High-throughput

0.479

High

696141

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

7

High-throughput

0.479

High

768831

RFA3
Replication protein A 14 kDa subunit

1

8

High-throughput

0.479

High

799372

BRCA1
Breast cancer type 1 susceptibility protein

1

11

High-throughput

0.479

High

800025

COIL
Coilin

1

2

High-throughput

0.479

High

831192

CCNF
Cyclin-F

1

7

High-throughput

0.479

High

879339

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

11

High-throughput

0.479

High

935586

MFAP1
Microfibrillar-associated protein 1

1

2

High-throughput

0.479

High

943289

RBM11
Splicing regulator RBM11

1

6

High-throughput

0.479

High

986620

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

3

High-throughput

0.479

High

1004380

NOP14
Nucleolar protein 14

1

3

High-throughput

0.479

High

1004937

RNF4
E3 ubiquitin-protein ligase RNF4

1

6

High-throughput

0.479

High

1032213

EXOSX
Exosome complex component 10

1

6

High-throughput

0.479

High

1035827

KIF23
Kinesin-like protein KIF23

1

14

High-throughput

0.479

High

1040884

MECOM
Histone-lysine N-methyltransferase MECOM

1

2

High-throughput

0.479

High

1043723

CEBPZ
CCAAT/enhancer-binding protein zeta

1

2

High-throughput

0.479

High

1087479

GRSF1
G-rich sequence factor 1

1

20

High-throughput

0.479

High

1100201

TIF1B
Transcription intermediary factor 1-beta

1

10

High-throughput

0.479

High

1107086

BIRC3
Baculoviral IAP repeat-containing protein 3

1

10

High-throughput

0.479

High

1117626

NOG2
Nucleolar GTP-binding protein 2

1

7

High-throughput

0.479

High

1126831

SLBP
Histone RNA hairpin-binding protein

1

1

High-throughput

0.479

High

1130950

BMS1
Ribosome biogenesis protein BMS1 homolog

1

9

High-throughput

0.479

High

1134506

NOLC1
Nucleolar and coiled-body phosphoprotein 1

1

7

High-throughput

0.479

High

1137920

TNIP1
TNFAIP3-interacting protein 1

1

20

High-throughput

0.479

High

1146760

PCBP1
Poly(rC)-binding protein 1

1

7

High-throughput

0.479

High

1168546

KNOP1
Lysine-rich nucleolar protein 1

1

1

High-throughput

0.479

High

1179345

TSR1
Pre-rRNA-processing protein TSR1 homolog

1

6

High-throughput

0.479

High

1191457

GRDN
Girdin

1

20

High-throughput

0.479

High

1197663

MIDN
Midnolin

1

1

High-throughput

0.479

High

1198623

NCBP3
Nuclear cap-binding protein subunit 3

1

1

High-throughput

0.479

High

1247961

ANR11
Ankyrin repeat domain-containing protein 11

1

11

High-throughput

0.479

High

1260521

NOL8
Nucleolar protein 8

1

1

High-throughput

0.479

High

1271775

MEPCE
7SK snRNA methylphosphate capping enzyme

1

2

High-throughput

0.479

High

1312360

SIR2
NAD-dependent protein deacetylase sirtuin-2

1

9

High-throughput

0.479

High

1331757

JMY
Junction-mediating and -regulatory protein

1

1

High-throughput

0.479

High

1332202

KRI1
Protein KRI1 homolog

1

4

High-throughput

0.479

High

1341118

WDR36
WD repeat-containing protein 36

1

19

High-throughput

0.479

High

1346878

SNIP1
Smad nuclear-interacting protein 1

1

4

High-throughput

0.479

High

1361203

DNJC9
DnaJ homolog subfamily C member 9

1

12

High-throughput

0.479

High

1364196

TOPB1
DNA topoisomerase 2-binding protein 1

1

13

High-throughput

0.479

High

1366965

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

1368348

REQU
Zinc finger protein ubi-d4

1

20

High-throughput

0.479

High

1381567

CHCH1
Small ribosomal subunit protein mS37

1

2

High-throughput

0.479

High

1381568

DCPS
m7GpppX diphosphatase

1

1

High-throughput

0.479

High

1381571

SIR1
NAD-dependent protein deacetylase sirtuin-1

1

9

High-throughput

0.479

High

1381573

LTV1
Protein LTV1 homolog

1

1

High-throughput

0.479

High

1381574

AURKB
Aurora kinase B

1

4

High-throughput

0.479

High

1381576

RING2
E3 ubiquitin-protein ligase RING2

1

18

High-throughput

0.479

High

1381580

NOL10
Nucleolar protein 10

1

3

High-throughput

0.479

High

1381581

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

3

High-throughput

0.479

High

1381582

NAT10
RNA cytidine acetyltransferase

1

2

High-throughput

0.479

High

1381586

HEAT1
HEAT repeat-containing protein 1

1

4

High-throughput

0.479

High

1381591

ECT2
Protein ECT2

1

18

High-throughput

0.479

High

1381592

CLSPN
Claspin

1

4

High-throughput

0.479

High

1381595

BRD7
Bromodomain-containing protein 7

1

20

High-throughput

0.479

High

1381598

SAS10
Something about silencing protein 10

1

2

High-throughput

0.479

High

1381599

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

9

High-throughput

0.479

High

1381603

SDA1
Protein SDA1 homolog

1

1

High-throughput

0.479

High

1381604

RBM28
RNA-binding protein 28

1

6

High-throughput

0.479

High

1381606

TLS1
Splicing factor C9orf78

1

4

High-throughput

0.479

High

1381611

ZRAN1
Ubiquitin thioesterase ZRANB1

1

7

High-throughput

0.479

High

1381618

RBM19
Probable RNA-binding protein 19

1

8

High-throughput

0.479

High

1381619

LAS1L
Ribosomal biogenesis protein LAS1L

1

2

High-throughput

0.479

High

1337407

SRFB1
Serum response factor-binding protein 1

1

0

High-throughput

0.458

High

106414

APRIO
Alternative prion protein

1

6

Small-scale

0.457

High

404866

PRIO
Major prion protein

1

1

Small-scale

0.457

High

165066

RPC1
DNA-directed RNA polymerase III subunit RPC1

1

2

High-throughput

0.445

High

316421

RMP
Unconventional prefoldin RPB5 interactor 1

1

6

High-throughput

0.445

High

430208

JUN
Transcription factor Jun

1

12

High-throughput

0.445

High

877463

MASP1
Mannan-binding lectin serine protease 1

1

1

Small-scale

0.445

High

1054628

PSME1
Proteasome activator complex subunit 1

1

2

High-throughput

0.445

High

1130373

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

6

High-throughput

0.445

High

1145312

RNPS1
RNA-binding protein with serine-rich domain 1

1

10

High-throughput

0.445

High

1381605

PIHD1
PIH1 domain-containing protein 1

1

3

High-throughput

0.445

High

242514

PRKN
E3 ubiquitin-protein ligase parkin

1

16

High-throughput

0.437

High

272371

OBSL1
Obscurin-like protein 1

1

8

High-throughput

0.437

High

340199

PCNT
Pericentrin

1

16

High-throughput

0.437

High

888476

TSP3
Thrombospondin-3

1

1

High-throughput

0.437

High

1140661

KIF14
Kinesin-like protein KIF14

1

10

High-throughput

0.437

High

1201866

PKHG4
Puratrophin-1

1

6

High-throughput

0.437

High

1351372

DLG5
Disks large homolog 5

1

2

High-throughput

0.437

High

1381569

ENTR1
Endosome-associated-trafficking regulator 1

1

1

High-throughput

0.437

High

1381584

CHM4B
Charged multivesicular body protein 4b

1

8

High-throughput

0.437

High

1381588

CCSE2
Serine-rich coiled-coil domain-containing protein 2

1

1

High-throughput

0.437

High

1381593

ZDBF2
DBF4-type zinc finger-containing protein 2

1

1

High-throughput

0.437

High

1381613

XPO7
Exportin-7

1

13

High-throughput

0.437

High

1381615

CP131
Centrosomal protein of 131 kDa

1

9

High-throughput

0.437

High

1381616

PP6R1
Serine/threonine-protein phosphatase 6 regulatory subunit 1

1

7

High-throughput

0.437

High

1309434

APLF
Aprataxin and PNK-like factor

1

0

High-throughput

0.426

High

1381609

UXT
Protein UXT

1

0

High-throughput

0.426

High

154

A0A024R6X4
PLEKHG4

1

6

High-throughput

0.407

High

259025

DNJA2
DnaJ homolog subfamily A member 2

1

8

High-throughput

0.407

High

317470

GFPT2
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2

1

2

High-throughput

0.407

High

437757

HEPS
Serine protease hepsin

1

1

High-throughput

0.407

High

630332

TNR1B
Tumor necrosis factor receptor superfamily member 1B

1

3

High-throughput

0.407

High

1155021

ADIPO
Adiponectin

1

1

High-throughput

0.407

High

1195305

TB10B
TBC1 domain family member 10B

1

1

High-throughput

0.407

High

1199932

P5CR3
Pyrroline-5-carboxylate reductase 3

1

2

High-throughput

0.407

High

1216389

FAXC
Failed axon connections homolog

1

1

High-throughput

0.407

High

1358817

KBTB7
Kelch repeat and BTB domain-containing protein 7

1

5

High-throughput

0.407

High

1381578

EGFL8
Epidermal growth factor-like protein 8

1

2

High-throughput

0.407

High

1381587

RPAP3
RNA polymerase II-associated protein 3

1

18

High-throughput

0.407

High

1381572

CNRP1
CB1 cannabinoid receptor-interacting protein 1

3

0

High-throughput

0.347

High

282531

PAGE1
P antigen family member 1

2

0

High-throughput

0.313

High

281772

VP26A
Vacuolar protein sorting-associated protein 26A

1

0

High-throughput

0.279

Low

365771

KAD1
Adenylate kinase isoenzyme 1

1

0

High-throughput

0.279

Low

465856

MSMB
Beta-microseminoprotein

1

0

High-throughput

0.279

Low

598268

CL3L1
C-C motif chemokine 3-like 1

1

0

High-throughput

0.279

Low

652661

GNLY
Granulysin

1

0

High-throughput

0.232

Low

946581

EVA1C
Protein eva-1 homolog C

1

0

High-throughput

0.232

Low

1309137

MISP
Mitotic interactor and substrate of PLK1

1

0

High-throughput

0.232

Low

1326718

MIA40
Mitochondrial intermembrane space import and assembly protein 40

1

0

High-throughput

0.232

Low

1381602

PDRG1
p53 and DNA damage-regulated protein 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025