HitPredict

Interactor 1: DYL1 (P63167)
Dynein light chain 1, cytoplasmic (8 kDa dynein light chain) (DLC8) (Dynein light chain LC8-type 1) (Protein inhibitor of neuronal nitric oxide synthase) (PIN)
Gene: DYNLL1

Interactor 2: TLK2 (Q86UE8)
Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1) (HsHPK) (PKU-alpha) (Tousled-like kinase 2)
Gene: TLK2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.90	0.60	0.737

Property	Details
Experiments	26496610, 27173435, 33961781, 35271311, 32707033, 33323470
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 89 Hs			1 772
+	Hs
		1199515 DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26		TLK2_HUMAN (1-754): 0: 585: 100.00
+	Hs
		928515 DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00		TLK1_HUMAN (2-769): 4.34e-142: 438: 65.33
+	Hs
		1291323 DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26		TLK1_HUMAN (2-769): 4.34e-142: 438: 65.33
+	Hs
		568621 DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00		KAPCA_HUMAN (450-772): 2.68e-126: 383: 23.78
+	Hs
		568762 DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26		KAPCA_HUMAN (450-772): 2.68e-126: 383: 23.78
+	Hs
		331163 DNAL4_HUMAN (7-89): 1.89e-29: 102: 35.29		KCC2D_HUMAN (457-743): 5.04e-106: 335: 28.57