HitPredict

Interactor 1: WDR5 (P61964)
WD repeat-containing protein 5 (BMP2-induced 3-kb gene protein)
Gene: WDR5

Interactor 2: AUTS2 (Q8WXX7)
Autism susceptibility gene 2 protein
Gene: AUTS2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	25519132
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 334 Hs			1 1259
+	Hs
		903374 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		KMT2C_HUMAN (430-1258): 3.63e-13: 77: 9.23
+	Hs
		903229 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		NCOA6_HUMAN (63-1250): 4.76e-13: 76.3: 10.27
+	Hs
		903576 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		RERE_HUMAN (10-900): 6.62e-13: 75.9: 9.42
+	Hs
		152622 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		KMT2D_HUMAN (75-890): 1.52e-10: 68.4: 12.98
+	Hs
		903450 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		CIC_HUMAN (124-1255): 2.4e-10: 67.4: 9.34
+	Mm
		903669 WDR5_MOUSE (1-334): 2.77e-131: 379: 100.00		KMT2C_MOUSE (323-1230): 5.99e-10: 66.3: 9.64
+	Hs
		209436 PLRG1_HUMAN (2-333): 5.29e-85: 267: 26.05		MDC1_HUMAN (700-1257): 7.36e-10: 65.9: 8.20
+	Dm
		1370295 POC1_DROME (11-254): 9.16e-70: 224: 25.82		Q9VLS7_DROME (22-771): 3.6e-10: 67: 8.97
+	Hs
		152663 WDR5B_HUMAN (3-198): 4.87e-59: 194: 30.10		KMT2D_HUMAN (75-890): 1.52e-10: 68.4: 12.98
+	Hs
		1103013 SMU1_HUMAN (30-331): 7.66e-39: 145: 28.71		CIC_HUMAN (124-1255): 2.4e-10: 67.4: 9.34
+	Hs
		1281391 FBXW7_HUMAN (198-333): 4.06e-28: 116: 30.15		PRR36_HUMAN (16-718): 2.52e-14: 80.5: 11.16
+	Hs
		1057782 FBXW7_HUMAN (198-333): 4.06e-28: 116: 30.15		NCOA6_HUMAN (63-1250): 4.76e-13: 76.3: 10.27
+	Hs
		152678 FBXW7_HUMAN (198-333): 4.06e-28: 116: 30.15		KMT2D_HUMAN (75-890): 1.52e-10: 68.4: 12.98
+	Dm
		1370339 FBXW7_DROME (40-169): 6.72e-18: 86.7: 39.10		Q9VLS7_DROME (22-771): 3.6e-10: 67: 8.97
+	Hs
		1056932 SNR40_HUMAN (248-333): 6.9e-13: 70.4: 25.29		MDC1_HUMAN (700-1257): 7.36e-10: 65.9: 8.20
+	Hs
		1074805 TAF5_HUMAN (163-330): 6.22e-12: 68.6: 25.25		CIC_HUMAN (124-1255): 2.4e-10: 67.4: 9.34
+	Hs
		1264784 SNR40_HUMAN (248-333): 6.9e-13: 70.4: 25.29		TITIN_HUMAN (60-591): 1.15e-09: 65.3: 11.92